OSPA7_BORBG
ID OSPA7_BORBG Reviewed; 272 AA.
AC Q04968;
DT 01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1995, sequence version 1.
DT 25-MAY-2022, entry version 76.
DE RecName: Full=Outer surface protein A;
DE Short=OSPA;
DE Flags: Precursor;
GN Name=ospA;
OS Borreliella burgdorferi (Lyme disease spirochete) (Borrelia burgdorferi).
OG Plasmid lp54.
OC Bacteria; Spirochaetes; Spirochaetales; Borreliaceae; Borreliella.
OX NCBI_TaxID=139;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=19857;
RX PubMed=1356932; DOI=10.1128/iai.60.11.4856-4866.1992;
RA Wallich R., Helmes C., Schaible U.E., Lobet Y., Moter S.E., Kramer M.D.,
RA Simon M.M.;
RT "Evaluation of genetic divergence among Borrelia burgdorferi isolates by
RT use of OspA, fla, HSP60, and HSP70 gene probes.";
RL Infect. Immun. 60:4856-4866(1992).
CC -!- SUBCELLULAR LOCATION: Cell outer membrane; Lipid-anchor.
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DR EMBL; X68059; CAA48196.1; -; Genomic_DNA.
DR PIR; C49209; C49209.
DR AlphaFoldDB; Q04968; -.
DR SMR; Q04968; -.
DR GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0007155; P:cell adhesion; IDA:CACAO.
DR InterPro; IPR001809; OM_lipoprot_Borrelia.
DR InterPro; IPR023322; OM_lipoprot_dom_sf.
DR Pfam; PF00820; Lipoprotein_1; 1.
DR PRINTS; PR00968; OUTRSURFACE.
DR SUPFAM; SSF51087; SSF51087; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Cell outer membrane; Lipoprotein; Membrane; Palmitate; Plasmid; Signal.
FT SIGNAL 1..16
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT CHAIN 17..272
FT /note="Outer surface protein A"
FT /id="PRO_0000018080"
FT LIPID 17
FT /note="N-palmitoyl cysteine"
FT /evidence="ECO:0000305"
FT LIPID 17
FT /note="S-diacylglycerol cysteine"
FT /evidence="ECO:0000305"
SQ SEQUENCE 272 AA; 29152 MW; 334FD2EF05153BB0 CRC64;
MKKYLLGIGL ILALIACKQN VSSLDEKNSV SVDVPGGMKV LVSKEKNKDG KYDLMATVDN
VDLKGTSDKN NGSGILEGVK ADKSKVKLTV ADDLSKTTLE VLKEDGTVVS RKVTSKDKST
TEAKFNEKGE LSEKTMTRAN GTTLEYSQMT NEDNAAKAVE TLKNGIKFEG NLASGKTAVE
IKEGTVTLKR EIDKNGKVTV SLNDTASGSK KTASWQESTS TLTISANSKK TKDLVFLTNG
TITVQNYDSA GTKLEGSAAE IKKLDELKNA LR