ID   OSPA_BORBG              Reviewed;         273 AA.
AC   Q09087;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1995, sequence version 1.
DT   25-MAY-2022, entry version 74.
DE   RecName: Full=Outer surface protein A;
DE   Flags: Precursor;
GN   Name=ospA;
OS   Borreliella burgdorferi (Lyme disease spirochete) (Borrelia burgdorferi).
OG   Plasmid lp54.
OC   Bacteria; Spirochaetes; Spirochaetales; Borreliaceae; Borreliella.
OX   NCBI_TaxID=139;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=25015;
RX   PubMed=1545130;
RA   Fikrig E., Barthold S.W., Persing D.H., Sun X., Kantor F.S., Flavell R.A.;
RT   "Borrelia burgdorferi strain 25015: characterization of outer surface
RT   protein A and vaccination against infection.";
RL   J. Immunol. 148:2256-2260(1992).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 15-96.
RC   STRAIN=25015;
RA   Mathiesen D.A., Oliver J.H. Jr., Kolbert C.P., Tullson E.D.,
RA   Johnson B.J.B., Campbell G.L., Mitchell P.D., Reed K.D., Anderson J.F.,
RA   Lane R.S., Persing D.H.;
RL   Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane; Lipid-anchor.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AF230516; AAB21761.1; -; Genomic_DNA.
DR   EMBL; U65802; AAB39577.1; -; Genomic_DNA.
DR   PIR; A46460; A46460.
DR   AlphaFoldDB; Q09087; -.
DR   SMR; Q09087; -.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR001809; OM_lipoprot_Borrelia.
DR   InterPro; IPR023322; OM_lipoprot_dom_sf.
DR   Pfam; PF00820; Lipoprotein_1; 1.
DR   PRINTS; PR00968; OUTRSURFACE.
DR   SUPFAM; SSF51087; SSF51087; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Lipoprotein; Membrane; Palmitate; Plasmid; Signal.
FT   SIGNAL          1..16
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CHAIN           17..273
FT                   /note="Outer surface protein A"
FT                   /id="PRO_0000018075"
FT   LIPID           17
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000305"
FT   LIPID           17
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   273 AA;  29449 MW;  764F6146E29AD898 CRC64;
     MKKYLLGIGL ILALIACKQN VSSLDEKNSV SVDLPGEMKV LVSKEKDKDG KYSLMATVDK
     LELKGTSDKN NGSGVLEGVK ADKSKVKLTV SDDLSTTTLE VLKEDGKTLV SKKRTSKDKS
     STEEKFNEKG ELVEKIMARA NGTILEYTGI KSDGSGKAKE TLKEYVLEGT LTAEKATLVV
     KEGTVTLSKH ISKSGEVTAE LNDTDSTQAT KKTGKWDAGT STLTITVNNK KTKALVFTKQ
     DTITSQKYDS AGTNLEGTAV EIKTLDELKN ALR