ID   OSPB_BORBG              Reviewed;         295 AA.
AC   Q09090; Q44949;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1995, sequence version 1.
DT   25-MAY-2022, entry version 79.
DE   RecName: Full=Outer surface protein B;
DE   Flags: Precursor;
GN   Name=ospB;
OS   Borreliella burgdorferi (Lyme disease spirochete) (Borrelia burgdorferi).
OG   Plasmid lp54.
OC   Bacteria; Spirochaetes; Spirochaetales; Borreliaceae; Borreliella.
OX   NCBI_TaxID=139;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=B29;
RX   PubMed=1398118; DOI=10.1016/0378-1119(92)90021-g;
RA   Fellinger W., Redl B., Stoeffler G.;
RT   "Sequence of the complete osp operon encoding two major outer membrane
RT   proteins of a European Borrelia burgdorferi isolate (B29).";
RL   Gene 120:127-128(1992).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=G2;
RA   Rosa P.A., Hogan D., Margolis N.;
RT   "Molecular analysis of the major outer surface protein locus from a
RT   divergent Borrelia burgdorferi isolate from Europe.";
RL   Curr. Commun. Cell Mol. Biol. 6:95-110(1992).
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane; Lipid-anchor.
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DR   EMBL; M88764; AAA18509.1; -; Unassigned_DNA.
DR   EMBL; L19702; AAA88847.1; -; Genomic_DNA.
DR   PIR; JC1431; JC1431.
DR   AlphaFoldDB; Q09090; -.
DR   SMR; Q09090; -.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR001809; OM_lipoprot_Borrelia.
DR   InterPro; IPR023322; OM_lipoprot_dom_sf.
DR   Pfam; PF00820; Lipoprotein_1; 1.
DR   PRINTS; PR00968; OUTRSURFACE.
DR   SUPFAM; SSF51087; SSF51087; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Lipoprotein; Membrane; Palmitate; Plasmid; Signal.
FT   SIGNAL          1..16
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CHAIN           17..295
FT                   /note="Outer surface protein B"
FT                   /id="PRO_0000018082"
FT   LIPID           17
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   LIPID           17
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   VARIANT         236
FT                   /note="V -> A (in strain: G2)"
SQ   SEQUENCE   295 AA;  32027 MW;  317C6738C4E9B8F7 CRC64;
     MKQYLLGFTL VFALIACAQK GANPEQKGGD ADVLNTSKTE KYLNKNLPSE AEDLVSLFND
     SEIFVSKEKN KDGKYVLRAI VDTVELKGVA DKNDGSEGKL EGLKPDNSKV TMSISKDQNT
     ITIETRDSSN TKVASKVFKK DGSLTEESYK AGQLDSKKLT RSNKTTLEYS DMTNAENATT
     AIETLKNGIE FKGSLVGGKA TLQIVESTVT LTREIDKDGK LKIYLKDTAS SSKKTVSWND
     TDTLTISAEG KKTKDLVFLT DGTITVQNYD SASGTTLEGT ATEIKNLEAL KTALK