ID   OSTA1_CAEEL             Reviewed;         384 AA.
AC   O17204;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2003, sequence version 2.
DT   03-AUG-2022, entry version 106.
DE   RecName: Full=Organic solute transporter alpha-like protein 1;
DE   AltName: Full=Solute carrier family 51 subunit alpha homolog C;
GN   Name=osta-1; ORFNames=C01B12.4;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- FUNCTION: Probable transporter. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane
CC       protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the OST-alpha family. {ECO:0000305}.
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DR   EMBL; FO080084; CCD61134.1; -; Genomic_DNA.
DR   PIR; T32366; T32366.
DR   RefSeq; NP_493630.2; NM_061229.2.
DR   AlphaFoldDB; O17204; -.
DR   STRING; 6239.C01B12.4; -.
DR   PaxDb; O17204; -.
DR   EnsemblMetazoa; C01B12.4.1; C01B12.4.1; WBGene00015287.
DR   GeneID; 182062; -.
DR   KEGG; cel:CELE_C01B12.4; -.
DR   UCSC; C01B12.4; c. elegans.
DR   CTD; 182062; -.
DR   WormBase; C01B12.4; CE34642; WBGene00015287; osta-1.
DR   eggNOG; KOG2641; Eukaryota.
DR   HOGENOM; CLU_061874_1_0_1; -.
DR   InParanoid; O17204; -.
DR   OMA; WLANMSV; -.
DR   OrthoDB; 1345827at2759; -.
DR   PhylomeDB; O17204; -.
DR   PRO; PR:O17204; -.
DR   Proteomes; UP000001940; Chromosome II.
DR   Bgee; WBGene00015287; Expressed in larva and 3 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; ISS:UniProtKB.
DR   GO; GO:1990075; C:periciliary membrane compartment; IDA:WormBase.
DR   InterPro; IPR005178; Ostalpha/TMEM184C.
DR   PANTHER; PTHR23423; PTHR23423; 1.
DR   Pfam; PF03619; Solute_trans_a; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Glycoprotein; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..384
FT                   /note="Organic solute transporter alpha-like protein 1"
FT                   /id="PRO_0000331550"
FT   TOPO_DOM        1..38
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        39..59
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        60..70
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        71..91
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        92..93
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        94..114
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        115..165
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        166..186
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        187..202
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        203..223
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        224..240
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        241..261
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        262..273
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        274..294
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        295..384
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        11
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        28
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   384 AA;  44205 MW;  A613312368D136B4 CRC64;
     MEIVKTIIPH NRSYIEPPIP SATEWLANMS VMHVSCLTIA CVFVAITFLS SFFHLFFVLK
     YVSNERIRND MYALIFMFPI TTFASLVGMF IPRAAIFLYA VSLVYFMFTL FIMVTLLFNI
     FGGRQEMSAY LLQRNIRVNF TVPPLCFFKF LPTVESTDQN LRRIEWLVFQ TPIIRTLLEL
     VSVVVSMEQE GRRESVWFVF SQLMALLSMC IAFYGCYVMV PLGREKHAPY RFDFLFRTCD
     IAQCIYTIQK FVFEFAAAVG LITSDRYLPA AAKALWWASF MCTWEMMLLS ALCSYCLRPA
     KCKFFDLYPG NDMPALSARD GSNSRVPSFS RRLSIEYEPR IAGVMLEPPS RSSLSITPRD
     KIEDPTTVSY FADNFDSLSQ IQGQ