OSW7_YEAST
ID OSW7_YEAST Reviewed; 510 AA.
AC P43611; D6VTS2;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1995, sequence version 1.
DT 03-AUG-2022, entry version 137.
DE RecName: Full=Outer spore wall protein 7 {ECO:0000303|PubMed:23966878};
DE Flags: Precursor;
GN Name=OSW7 {ECO:0000303|PubMed:23966878};
GN OrderedLocusNames=YFR039C {ECO:0000312|SGD:S000001935};
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 204511 / S288c / AB972;
RX PubMed=8686381;
RX DOI=10.1002/(sici)1097-0061(199602)12:2<177::aid-yea896>3.0.co;2-a;
RA Eki T., Naitou M., Hagiwara H., Abe M., Ozawa M., Sasanuma S., Sasanuma M.,
RA Tsuchiya Y., Shibata T., Watanabe K., Ono A., Yamazaki M., Tashiro H.,
RA Hanaoka F., Murakami Y.;
RT "Fifteen open reading frames in a 30.8 kb region of the right arm of
RT chromosome VI from Saccharomyces cerevisiae.";
RL Yeast 12:177-190(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=7670463; DOI=10.1038/ng0795-261;
RA Murakami Y., Naitou M., Hagiwara H., Shibata T., Ozawa M., Sasanuma S.,
RA Sasanuma M., Tsuchiya Y., Soeda E., Yokoyama K., Yamazaki M., Tashiro H.,
RA Eki T.;
RT "Analysis of the nucleotide sequence of chromosome VI from Saccharomyces
RT cerevisiae.";
RL Nat. Genet. 10:261-268(1995).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [4]
RP LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
RX PubMed=14562106; DOI=10.1038/nature02046;
RA Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N.,
RA O'Shea E.K., Weissman J.S.;
RT "Global analysis of protein expression in yeast.";
RL Nature 425:737-741(2003).
RN [5]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-354, AND IDENTIFICATION BY
RP MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC STRAIN=ADR376;
RX PubMed=17330950; DOI=10.1021/pr060559j;
RA Li X., Gerber S.A., Rudner A.D., Beausoleil S.A., Haas W., Villen J.,
RA Elias J.E., Gygi S.P.;
RT "Large-scale phosphorylation analysis of alpha-factor-arrested
RT Saccharomyces cerevisiae.";
RL J. Proteome Res. 6:1190-1197(2007).
RN [6]
RP FUNCTION, AND DISRUPTION PHENOTYPE.
RX PubMed=23966878; DOI=10.1371/journal.pgen.1003700;
RA Lin C.P., Kim C., Smith S.O., Neiman A.M.;
RT "A highly redundant gene network controls assembly of the outer spore wall
RT in S. cerevisiae.";
RL PLoS Genet. 9:E1003700-E1003700(2013).
CC -!- FUNCTION: Involved in spore wall assembly.
CC {ECO:0000269|PubMed:23966878}.
CC -!- DISRUPTION PHENOTYPE: A combined deletion of the OSW7 and SHE10 has
CC reduced dityrosine incorporation in the outer spore wall.
CC {ECO:0000269|PubMed:23966878}.
CC -!- MISCELLANEOUS: Present with 3170 molecules/cell in log phase SD medium.
CC {ECO:0000269|PubMed:14562106}.
CC -!- SIMILARITY: Belongs to the OSW/SHE family. {ECO:0000305}.
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DR EMBL; D50617; BAA09278.1; -; Genomic_DNA.
DR EMBL; BK006940; DAA12482.1; -; Genomic_DNA.
DR PIR; S56294; S56294.
DR RefSeq; NP_116697.3; NM_001180004.3.
DR AlphaFoldDB; P43611; -.
DR BioGRID; 31197; 77.
DR DIP; DIP-912N; -.
DR IntAct; P43611; 1.
DR STRING; 4932.YFR039C; -.
DR iPTMnet; P43611; -.
DR MaxQB; P43611; -.
DR PaxDb; P43611; -.
DR PRIDE; P43611; -.
DR EnsemblFungi; YFR039C_mRNA; YFR039C; YFR039C.
DR GeneID; 850600; -.
DR KEGG; sce:YFR039C; -.
DR SGD; S000001935; OSW7.
DR VEuPathDB; FungiDB:YFR039C; -.
DR eggNOG; ENOG502S2G3; Eukaryota.
DR GeneTree; ENSGT00940000176455; -.
DR HOGENOM; CLU_050901_0_0_1; -.
DR InParanoid; P43611; -.
DR OMA; DINCTSK; -.
DR BioCyc; YEAST:G3O-30486-MON; -.
DR PRO; PR:P43611; -.
DR Proteomes; UP000002311; Chromosome VI.
DR RNAct; P43611; protein.
DR GO; GO:0005783; C:endoplasmic reticulum; HDA:SGD.
DR GO; GO:0030476; P:ascospore wall assembly; IGI:SGD.
PE 1: Evidence at protein level;
KW Phosphoprotein; Reference proteome; Signal; Sporulation.
FT SIGNAL 1..23
FT /evidence="ECO:0000255"
FT CHAIN 24..510
FT /note="Outer spore wall protein 7"
FT /id="PRO_0000202694"
FT REGION 167..195
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 171..195
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 354
FT /note="Phosphotyrosine"
FT /evidence="ECO:0007744|PubMed:17330950"
SQ SEQUENCE 510 AA; 59360 MW; 2A8BCC6F18EAFE83 CRC64;
MKAVFKVTTA LLACVFIARY LVCQQNGLGS FATDLQPICR HTEFSVGSLF DSKLVEGSAV
SDYLVGKYSQ SIKPLIERYP NSSLKRIMGY FYRFWYNIFS FLRLNELCCS LHSKLGPLLN
HLRIAWYYLK PYTDNVKNVL ENPFNSSTDW MKYGSFSADG TLTKPIFETD SETEDYEDDE
NENEDEDEDE DEDDVGIEDE NKEYEFDGVQ DGHGNSQLVT AAILQDLSKI IIGSNSHAEL
ETYEAESLKM EYEAWIKAID SKIHSAMALL DSEIQSVFEA EVQNKSIEIT RNLDDLNTTV
NEQLVFLDSK IKDINCTSKF DPVQNKIKYF DESGQVELEA YITKSSITSI LKNYKIHLLD
FEKSLFHSLD SFLTEMAKLA ESIRLENVEV YEEWGDVMIS QWSQRMAYMD VRGLHLEDQY
DPAYIEENHS NWLRFMELKK KVISERNRLV KHDLDMTLIL EWITKLKADF QNTKNNIQDT
FLQRMNTADT LFKNRELKEQ LEEEFVRQEH
