OTCC_AERCA
ID OTCC_AERCA Reviewed; 30 AA.
AC P11726;
DT 01-OCT-1989, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1989, sequence version 1.
DT 25-MAY-2022, entry version 83.
DE RecName: Full=Ornithine carbamoyltransferase, catabolic;
DE Short=OTCase;
DE EC=2.1.3.3;
DE Flags: Fragment;
GN Name=arcB;
OS Aeromonas caviae (Aeromonas punctata).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Aeromonadales;
OC Aeromonadaceae; Aeromonas.
OX NCBI_TaxID=648;
RN [1]
RP PROTEIN SEQUENCE.
RC STRAIN=NCIMB 9232 / CDC 2030-53 / LMG 3742 / RH 1;
RX PubMed=3968036; DOI=10.1128/jb.161.2.714-719.1985;
RA Falmagne P., Portetelle D., Stalon V.;
RT "Immunological and structural relatedness of catabolic ornithine
RT carbamoyltransferases and the anabolic enzymes of enterobacteria.";
RL J. Bacteriol. 161:714-719(1985).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=carbamoyl phosphate + L-ornithine = H(+) + L-citrulline +
CC phosphate; Xref=Rhea:RHEA:19513, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:46911, ChEBI:CHEBI:57743,
CC ChEBI:CHEBI:58228; EC=2.1.3.3;
CC -!- PATHWAY: Amino-acid degradation; L-arginine degradation via ADI
CC pathway; carbamoyl phosphate from L-arginine: step 2/2.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the aspartate/ornithine carbamoyltransferase
CC superfamily. OTCase family. {ECO:0000305}.
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DR AlphaFoldDB; P11726; -.
DR SMR; P11726; -.
DR UniPathway; UPA00254; UER00365.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0016597; F:amino acid binding; IEA:InterPro.
DR GO; GO:0004585; F:ornithine carbamoyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0019547; P:arginine catabolic process to ornithine; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.40.50.1370; -; 1.
DR InterPro; IPR036901; Asp/Orn_carbamoylTrfase_sf.
PE 1: Evidence at protein level;
KW Arginine metabolism; Cytoplasm; Direct protein sequencing; Transferase.
FT CHAIN 1..>30
FT /note="Ornithine carbamoyltransferase, catabolic"
FT /id="PRO_0000112871"
FT NON_TER 30
SQ SEQUENCE 30 AA; 3654 MW; 673CB989FE72F9C1 CRC64;
AFNLRNRNFL KLLDFTPREI QYMIDLAIDL