ID   OTOGL_PONAB             Reviewed;         708 AA.
AC   Q5RCW9;
DT   16-DEC-2008, integrated into UniProtKB/Swiss-Prot.
DT   06-FEB-2013, sequence version 2.
DT   25-MAY-2022, entry version 62.
DE   RecName: Full=Otogelin-like protein;
DE   Flags: Fragment;
GN   Name=OTOGL;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Kidney;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the otogelin family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAH90388.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; CR858149; CAH90388.1; ALT_INIT; mRNA.
DR   RefSeq; NP_001125189.1; NM_001131717.1.
DR   AlphaFoldDB; Q5RCW9; -.
DR   STRING; 9601.ENSPPYP00000005470; -.
DR   GeneID; 100172080; -.
DR   KEGG; pon:100172080; -.
DR   CTD; 283310; -.
DR   eggNOG; KOG1216; Eukaryota.
DR   InParanoid; Q5RCW9; -.
DR   Proteomes; UP000001595; Unplaced.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0007605; P:sensory perception of sound; IEA:InterPro.
DR   InterPro; IPR006207; Cys_knot_C.
DR   InterPro; IPR030110; Otogl.
DR   InterPro; IPR036084; Ser_inhib-like_sf.
DR   InterPro; IPR014853; Unchr_dom_Cys-rich.
DR   InterPro; IPR001846; VWF_type-D.
DR   PANTHER; PTHR11339:SF225; PTHR11339:SF225; 2.
DR   Pfam; PF00094; VWD; 1.
DR   SMART; SM00832; C8; 1.
DR   SMART; SM00041; CT; 1.
DR   SUPFAM; SSF57567; SSF57567; 1.
DR   PROSITE; PS01225; CTCK_2; 1.
DR   PROSITE; PS51233; VWFD; 1.
PE   2: Evidence at transcript level;
KW   Disulfide bond; Glycoprotein; Reference proteome; Secreted.
FT   CHAIN           <1..708
FT                   /note="Otogelin-like protein"
FT                   /id="PRO_0000358331"
FT   DOMAIN          <1..113
FT                   /note="VWFD"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00580"
FT   DOMAIN          616..708
FT                   /note="CTCK"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00039"
FT   CARBOHYD        553
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   DISULFID        616..672
FT                   /evidence="ECO:0000250"
FT   DISULFID        637..686
FT                   /evidence="ECO:0000250"
FT   DISULFID        648..703
FT                   /evidence="ECO:0000250"
FT   DISULFID        652..705
FT                   /evidence="ECO:0000250"
FT   NON_TER         1
SQ   SEQUENCE   708 AA;  80300 MW;  C89AF4F2B9F60916 CRC64;
     KIIVNRLARK VEVDSIVVPL PFSSQELSIE DSGSMYVITT PAGLIIKWSH LTGIIDIHFG
     FRFNLSSYTE GLCGICNEDP DDDLRMQNGT IITNMEDIGL FIESWEIEKS FEVTMRRPVR
     NCTEHDCSQC IDLLNRRIFI PCHDKVSPED FCEKMWINYT YFWNYECDAL SAYVALCNKF
     DICIQWRTPD YCSLSCPEGK EYQPCVRPCE ARTCLNQWFY GHSSCLNLRE DCACKDGTIL
     HRPHSTQCIP EKECACTDSE DQPRTAGEIW NGGIDECALY KCLENGSVIP IEPDCDEEPT
     PVCEREAEVV MGIIDKWTCC SKEVCGCDAT LCEPTIPTCT NGEKLIVGHS PLSCCPQYKC
     ECDPLKCPSI STPECREDQF MIQVQQEEPC CFSPFCVCES CTKPVPLCHD GEFLTVDLNS
     THFCCPQYYC VCEPNLCPMP LLNCAEDMNL VKENVFGQCC PTWHCEKDDV CVFQEVSVLN
     PGQSMIKYLE EDFCYTIECL EEKDNHTGFH TLNFTLVNCS KKCDVHQVYT PSPSDYDCCG
     TCKNVSCKFH MENGTSVVYV VGSTWHYNCT TYECVKTDEG AIILNYTMVC PPFNETECKM
     NEGIVKLYNE GCCKICKREE RICQKVIIKS VIRKQDCMSQ SLINVASCDG KCPSATIYNI
     NIGSHLRFCK CCRENGVRNL SVPLYCSGNG TEIMYTLQEP IDCTCQWN