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OTOR_CHICK
ID   OTOR_CHICK              Reviewed;         132 AA.
AC   Q9I8P6;
DT   21-FEB-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   03-AUG-2022, entry version 104.
DE   RecName: Full=Otoraplin;
DE   Flags: Precursor;
GN   Name=OTOR;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=10873378; DOI=10.1006/geno.2000.6224;
RA   Robertson N.G., Heller S., Lin J.S., Resendes B.L., Weremowicz S.,
RA   Denis C.S., Bell A.M., Hudspeth A.J., Morton C.C.;
RT   "A novel conserved cochlear gene, OTOR: identification, expression
RT   analysis, and chromosomal mapping.";
RL   Genomics 66:242-248(2000).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC   -!- TISSUE SPECIFICITY: Highly expressed in cochlea.
CC   -!- SIMILARITY: Belongs to the MIA/OTOR family. {ECO:0000305}.
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DR   EMBL; AF233518; AAF82727.1; -; mRNA.
DR   RefSeq; NP_990063.1; NM_204732.1.
DR   AlphaFoldDB; Q9I8P6; -.
DR   SMR; Q9I8P6; -.
DR   STRING; 9031.ENSGALP00000014195; -.
DR   PaxDb; Q9I8P6; -.
DR   Ensembl; ENSGALT00000014211; ENSGALP00000014195; ENSGALG00000008732.
DR   GeneID; 395484; -.
DR   KEGG; gga:395484; -.
DR   CTD; 64693; -.
DR   VEuPathDB; HostDB:geneid_395484; -.
DR   eggNOG; ENOG502S18Q; Eukaryota.
DR   GeneTree; ENSGT00950000182767; -.
DR   HOGENOM; CLU_158739_0_1_1; -.
DR   InParanoid; Q9I8P6; -.
DR   OMA; LCADDDC; -.
DR   OrthoDB; 1421159at2759; -.
DR   PhylomeDB; Q9I8P6; -.
DR   TreeFam; TF332724; -.
DR   PRO; PR:Q9I8P6; -.
DR   Proteomes; UP000000539; Chromosome 3.
DR   Bgee; ENSGALG00000008732; Expressed in skeletal muscle tissue and 5 other tissues.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0001502; P:cartilage condensation; IBA:GO_Central.
DR   CDD; cd11891; MIAL; 1.
DR   InterPro; IPR042801; OTOR.
DR   InterPro; IPR035554; Otoraplin_SH3.
DR   InterPro; IPR036028; SH3-like_dom_sf.
DR   InterPro; IPR001452; SH3_domain.
DR   PANTHER; PTHR47146; PTHR47146; 1.
DR   Pfam; PF07653; SH3_2; 1.
DR   SMART; SM00326; SH3; 1.
DR   SUPFAM; SSF50044; SSF50044; 1.
DR   PROSITE; PS50002; SH3; 1.
PE   2: Evidence at transcript level;
KW   Disulfide bond; Reference proteome; Secreted; SH3 domain; Signal.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000255"
FT   CHAIN           24..132
FT                   /note="Otoraplin"
FT                   /id="PRO_0000019035"
FT   DOMAIN          42..114
FT                   /note="SH3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00192"
FT   DISULFID        35..40
FT                   /evidence="ECO:0000250"
FT   DISULFID        58..131
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   132 AA;  15177 MW;  9D1CB07FD353CE1C CRC64;
     MTQRVYSIVL FLCFGLMNPF ATGIFMDKLA SKKLCADDDC VYTISLVRAE EDYNAPDCRF
     INIKKGQLIY VYSKLVKEKE SGEFWAGSVY GEEYEDHMGT VGYFPRSLVS EQHVYQEANK
     TIPTTDIDFF CE
 
 
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