ID   ASCL_ALLCG              Reviewed;           7 AA.
AC   P84071;
DT   16-AUG-2004, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 22.
DE   RecName: Full=Ascalin;
DE   Flags: Fragment;
OS   Allium cepa var. aggregatum (Shallot) (Allium ascalonicum).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Asparagales; Amaryllidaceae;
OC   Allioideae; Allieae; Allium.
OX   NCBI_TaxID=28911;
RN   [1] {ECO:0000305}
RP   PROTEIN SEQUENCE, AND FUNCTION.
RC   TISSUE=Bulb {ECO:0000269|PubMed:12126728};
RX   PubMed=12126728; DOI=10.1016/s0196-9781(02)00032-3;
RA   Wang H.X., Ng T.B.;
RT   "Ascalin, a new anti-fungal peptide with human immunodeficiency virus type
RT   1 reverse transcriptase-inhibiting activity from shallot bulbs.";
RL   Peptides 23:1025-1029(2002).
CC   -!- FUNCTION: Has antifungal activity against B.cinerea. Inhibits HIV-1
CC       reverse transcriptase. {ECO:0000269|PubMed:12126728}.
CC   -!- MISCELLANEOUS: Inhibits HIV-1 reverse transcriptase with an IC(50) of
CC       10 uM.
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DR   GO; GO:0050832; P:defense response to fungus; IEA:UniProtKB-KW.
DR   GO; GO:0031640; P:killing of cells of another organism; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Antimicrobial; Direct protein sequencing; Fungicide.
FT   PEPTIDE         1..>7
FT                   /note="Ascalin"
FT                   /id="PRO_0000045090"
FT   NON_TER         7
FT                   /evidence="ECO:0000303|PubMed:12126728"
SQ   SEQUENCE   7 AA;  712 MW;  687866D87EA6CB30 CRC64;
     YQCGQGG