OV16_ONCVO
ID OV16_ONCVO Reviewed; 197 AA.
AC P31729;
DT 01-JUL-1993, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1996, sequence version 2.
DT 25-MAY-2022, entry version 77.
DE RecName: Full=OV-16 antigen;
DE Flags: Precursor;
GN Name=OV16;
OS Onchocerca volvulus.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Onchocerca.
OX NCBI_TaxID=6282;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=1689459; DOI=10.1016/0166-6851(90)90016-f;
RA Lobos E., Altmann M., Mengod G., Weiss N., Rudin W., Karam M.;
RT "Identification of an Onchocerca volvulus cDNA encoding a low-molecular-
RT weight antigen uniquely recognized by onchocerciasis patient sera.";
RL Mol. Biochem. Parasitol. 39:135-146(1990).
CC -!- TISSUE SPECIFICITY: Hypodermis, cuticle and uterus.
CC -!- SIMILARITY: Belongs to the phosphatidylethanolamine-binding protein
CC family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAA29411.1; Type=Frameshift; Evidence={ECO:0000305};
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DR EMBL; M27807; AAA29411.1; ALT_FRAME; mRNA.
DR PIR; A44947; A44947.
DR PIR; PC4215; PC4215.
DR PIR; PC4216; PC4216.
DR AlphaFoldDB; P31729; -.
DR SMR; P31729; -.
DR STRING; 6282.P31729; -.
DR MEROPS; I51.002; -.
DR HOGENOM; CLU_043994_3_0_1; -.
DR Proteomes; UP000024404; Unassembled WGS sequence.
DR CDD; cd00866; PEBP_euk; 1.
DR Gene3D; 3.90.280.10; -; 1.
DR InterPro; IPR008914; PEBP.
DR InterPro; IPR036610; PEBP-like_sf.
DR InterPro; IPR035810; PEBP_euk.
DR InterPro; IPR001858; Phosphatidylethanolamine-bd_CS.
DR PANTHER; PTHR11362; PTHR11362; 1.
DR Pfam; PF01161; PBP; 1.
DR SUPFAM; SSF49777; SSF49777; 1.
DR PROSITE; PS01220; PBP; 1.
PE 2: Evidence at transcript level;
KW Glycoprotein; Reference proteome; Signal.
FT SIGNAL 1..16
FT /evidence="ECO:0000255"
FT CHAIN 17..197
FT /note="OV-16 antigen"
FT /id="PRO_0000023282"
FT CARBOHYD 56
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 61
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 119
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 124
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 197 AA; 21773 MW; 99988F20FDE854E3 CRC64;
MHCLQVVIAI VLYSFGKISA ENANCKKCTP MLVDSAFKEH GIVPDVVSTA PTKLVNVSYN
NLTVNLGNEL TPTQVKNQPT KVSWDAEPGA LYTLVMTDPD APSRKNPVFR EWHHWLIINI
SGQNVSSGTV LSDYIGSGPR KGTGLHRYVF LVYKQPGSIT DTQHGGNRRN FKVMDFANKH
HLGNPVAGNF FQAKHED