ID   OV17_ONCVO              Reviewed;         164 AA.
AC   P36991;
DT   01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1994, sequence version 1.
DT   25-MAY-2022, entry version 54.
DE   RecName: Full=OV-17 antigen;
DE   AltName: Full=Immunodominant hypodermal antigen;
DE   Flags: Precursor;
GN   Name=OV17;
OS   Onchocerca volvulus.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Onchocerca.
OX   NCBI_TaxID=6282;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=L3 / Rainforest;
RX   PubMed=8253155; DOI=10.1006/expr.1993.1101;
RA   Bradley J.E., Tuan R.S., Shepley K.J., Tree T.I.M., Maizels R.M., Helm R.,
RA   Gregory W.F., Unnasch T.R.;
RT   "Onchocerca volvulus: characterization of an immunodominant hypodermal
RT   antigen present in adult and larval parasites.";
RL   Exp. Parasitol. 77:414-424(1993).
CC   -!- TISSUE SPECIFICITY: High levels in the hypodermal layer of the adult
CC       female.
CC   -!- DEVELOPMENTAL STAGE: Present in larvae and in adult parasites.
CC   -!- SIMILARITY: Belongs to the SXP/RAL-2 family. {ECO:0000305}.
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DR   EMBL; U00693; AAA18283.1; -; mRNA.
DR   PIR; A60758; A60758.
DR   AlphaFoldDB; P36991; -.
DR   SMR; P36991; -.
DR   EnsemblMetazoa; OVOC9988; OVOC9988; WBGene00246797.
DR   HOGENOM; CLU_1621016_0_0_1; -.
DR   OMA; DAQIDQK; -.
DR   Proteomes; UP000024404; Unassembled WGS sequence.
DR   InterPro; IPR003677; ANIS5_cation-bd.
DR   Pfam; PF02520; DUF148; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome; Signal.
FT   SIGNAL          1..16
FT                   /evidence="ECO:0000255"
FT   CHAIN           17..164
FT                   /note="OV-17 antigen"
FT                   /id="PRO_0000021979"
FT   REGION          24..43
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   164 AA;  18784 MW;  5D405CE0DFBDA9CE CRC64;
     MKFVILLTIG LLVVAAIPQR RQQQQQQQQQ QQRDEREIPP FLEGAPPSVI DEFYNLLKTD
     ENKTDQQTEA DVEAFINRLG GSYKVRFTQF MEEVKKARAD YERIHQQAVA RFSPAAKDAD
     ARMSAIADSP HLTTRQKSQQ IQAIMDSLSE SVRREIINAL SPQE