ID   OV39_ONCVO              Reviewed;         115 AA.
AC   P31730;
DT   01-JUL-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1993, sequence version 1.
DT   25-MAY-2022, entry version 38.
DE   RecName: Full=OV39 antigen;
DE   Flags: Fragment;
GN   Name=OV39;
OS   Onchocerca volvulus.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Onchocerca.
OX   NCBI_TaxID=6282;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=Isolate Guatemala, and Isolate Sierra Leone;
RX   PubMed=2056276; DOI=10.1084/jem.174.1.169;
RA   Braun G., McKechnie N.M., Connor V., Gilbert C.E., Engelbrecht F.,
RA   Whitworth J.A., Taylor D.W.;
RT   "Immunological crossreactivity between a cloned antigen of Onchocerca
RT   volvulus and a component of the retinal pigment epithelium.";
RL   J. Exp. Med. 174:169-177(1991).
CC   -!- MISCELLANEOUS: Antibodies against this antigen can recognize a human
CC       retinal pigment epithelium antigen explaining in part the retinal
CC       damage caused in onchocerciasis.
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DR   EMBL; X59074; CAA41797.1; -; mRNA.
DR   PIR; PH0861; PH0861.
DR   AlphaFoldDB; P31730; -.
DR   STRING; 6282.P31730; -.
DR   PRIDE; P31730; -.
DR   HOGENOM; CLU_086462_0_0_1; -.
DR   Proteomes; UP000024404; Unassembled WGS sequence.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           <1..>115
FT                   /note="OV39 antigen"
FT                   /id="PRO_0000058105"
FT   VARIANT         59
FT                   /note="R -> Q (in strain: Isolate Guatemala)"
FT   NON_TER         1
FT   NON_TER         115
SQ   SEQUENCE   115 AA;  13086 MW;  8068C6A03E5B1FFF CRC64;
     IEAAKSSNNC AVPPFVGDLP IAENKEVLSI WKDYKSGEDC SNQRRETQQV IDDLPDEVRA
     MVFGRLPSFL NGASTDVKKM FRAIMYNRTL NYDLKKQELS KLAEEILSKK QLAEF