ID   OVCA2_BOVIN             Reviewed;         227 AA.
AC   Q3SZ07;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2005, sequence version 1.
DT   03-AUG-2022, entry version 81.
DE   RecName: Full=Esterase OVCA2;
DE            EC=3.1.2.- {ECO:0000305};
DE   AltName: Full=Ovarian cancer-associated gene 2 protein homolog;
GN   Name=OVCA2;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Thymus;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the LovG family. {ECO:0000305}.
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DR   EMBL; BC103277; AAI03278.1; -; mRNA.
DR   RefSeq; NP_001029773.1; NM_001034601.2.
DR   AlphaFoldDB; Q3SZ07; -.
DR   SMR; Q3SZ07; -.
DR   STRING; 9913.ENSBTAP00000012341; -.
DR   ESTHER; bovin-OVCA2; FSH1.
DR   PaxDb; Q3SZ07; -.
DR   PRIDE; Q3SZ07; -.
DR   Ensembl; ENSBTAT00000012341; ENSBTAP00000012341; ENSBTAG00000047926.
DR   GeneID; 513845; -.
DR   KEGG; bta:513845; -.
DR   CTD; 124641; -.
DR   VEuPathDB; HostDB:ENSBTAG00000047926; -.
DR   VGNC; VGNC:32504; OVCA2.
DR   eggNOG; KOG2551; Eukaryota.
DR   GeneTree; ENSGT00390000003541; -.
DR   HOGENOM; CLU_051938_2_3_1; -.
DR   InParanoid; Q3SZ07; -.
DR   OMA; EEPTVCR; -.
DR   OrthoDB; 1190789at2759; -.
DR   TreeFam; TF313006; -.
DR   Proteomes; UP000009136; Chromosome 19.
DR   Bgee; ENSBTAG00000047926; Expressed in adenohypophysis and 106 other tissues.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0016787; F:hydrolase activity; IBA:GO_Central.
DR   GO; GO:0032526; P:response to retinoic acid; IBA:GO_Central.
DR   Gene3D; 3.40.50.1820; -; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR005645; FSH_dom.
DR   Pfam; PF03959; FSH1; 1.
DR   SUPFAM; SSF53474; SSF53474; 1.
PE   2: Evidence at transcript level;
KW   Hydrolase; Reference proteome.
FT   CHAIN           1..227
FT                   /note="Esterase OVCA2"
FT                   /id="PRO_0000300875"
FT   ACT_SITE        119
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000250|UniProtKB:P38777"
FT   ACT_SITE        179
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000250|UniProtKB:P38777"
FT   ACT_SITE        206
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000250|UniProtKB:P38777"
SQ   SEQUENCE   227 AA;  24168 MW;  51584A790436C9A2 CRC64;
     MAAQPLLRIL CLAGFRQSER GFREKTGALR KALRGRAELV CLSGPHPVVD AAGSEGARPD
     SGPCPPEEQP QGWWFSEQEA DVFLALEEPT ACRGLEEALE TVAQALNKLG PFDGILGFSQ
     GAALAALVCA LGQGGDPRFP LPRFVILVSG FCPRGLGLME PIMQGPLSLP SLHVFGDTDG
     VIPSQESMQL CSRFDGAVTL THSGGHFIPA AAPQRQAYLK FLDQFAD