ID   OVCA2_DANRE             Reviewed;         227 AA.
AC   Q503Y4;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   07-JUN-2005, sequence version 1.
DT   03-AUG-2022, entry version 87.
DE   RecName: Full=Esterase OVCA2;
DE            EC=3.1.2.- {ECO:0000305};
DE   AltName: Full=Ovarian cancer-associated gene 2 protein homolog;
GN   Name=ovca2; ORFNames=zgc:110011;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Eye;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the LovG family. {ECO:0000305}.
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DR   EMBL; BC095129; AAH95129.1; -; mRNA.
DR   RefSeq; NP_001018391.1; NM_001020555.1.
DR   AlphaFoldDB; Q503Y4; -.
DR   SMR; Q503Y4; -.
DR   STRING; 7955.ENSDARP00000051111; -.
DR   ESTHER; danre-OVCA2; FSH1.
DR   PaxDb; Q503Y4; -.
DR   Ensembl; ENSDART00000167376; ENSDARP00000133226; ENSDARG00000103748.
DR   GeneID; 553576; -.
DR   KEGG; dre:553576; -.
DR   CTD; 124641; -.
DR   ZFIN; ZDB-GENE-050522-115; ovca2.
DR   eggNOG; KOG2551; Eukaryota.
DR   GeneTree; ENSGT00390000003541; -.
DR   HOGENOM; CLU_051938_2_3_1; -.
DR   InParanoid; Q503Y4; -.
DR   OMA; EEPTVCR; -.
DR   OrthoDB; 1190789at2759; -.
DR   PhylomeDB; Q503Y4; -.
DR   TreeFam; TF313006; -.
DR   PRO; PR:Q503Y4; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 10.
DR   Bgee; ENSDARG00000103748; Expressed in ovary and 24 other tissues.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0016787; F:hydrolase activity; IBA:GO_Central.
DR   GO; GO:0032526; P:response to retinoic acid; IBA:GO_Central.
DR   Gene3D; 3.40.50.1820; -; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR005645; FSH_dom.
DR   Pfam; PF03959; FSH1; 1.
DR   SUPFAM; SSF53474; SSF53474; 1.
PE   2: Evidence at transcript level;
KW   Hydrolase; Reference proteome.
FT   CHAIN           1..227
FT                   /note="Esterase OVCA2"
FT                   /id="PRO_0000300878"
FT   ACT_SITE        120
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000250|UniProtKB:P38777"
FT   ACT_SITE        180
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000250|UniProtKB:P38777"
FT   ACT_SITE        207
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000250|UniProtKB:P38777"
SQ   SEQUENCE   227 AA;  25277 MW;  D8A5454A2F0D3644 CRC64;
     MSAVPLRILC IHGYRQNGNS FREKTGALRK LLKKQVELVF ISAPHQVPAI QEENCGTNQQ
     SQTVSVGDED QRGWWFSDVQ ARSFNAKQDC ESSLGLEESI EAVKAALKDL GPFSGILGFS
     QGAALVAMLC ALQEQKLEPD FNFRFAILVA GFRSACLEHQ RFYEGPVITI PSLHVFGQDD
     RVIPEEMSRD LLPAFDGAQV LLHPGGHFVP AASSHRQTYQ DFLKRFQ