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OVOL3_MOUSE
ID   OVOL3_MOUSE             Reviewed;         189 AA.
AC   D3YYM0;
DT   25-JAN-2012, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 2.
DT   03-AUG-2022, entry version 78.
DE   RecName: Full=Putative transcription factor ovo-like protein 3;
GN   Name=Ovol3;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J;
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA   Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA   Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA   Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA   Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA   Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of the
RT   mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
CC   -!- FUNCTION: May act as a transcription regulator. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein
CC       family. {ECO:0000305}.
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DR   EMBL; AC149067; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   CCDS; CCDS80691.1; -.
DR   RefSeq; NP_001276746.1; NM_001289817.1.
DR   RefSeq; XP_011248918.1; XM_011250616.2.
DR   AlphaFoldDB; D3YYM0; -.
DR   SMR; D3YYM0; -.
DR   STRING; 10090.ENSMUSP00000140811; -.
DR   PhosphoSitePlus; D3YYM0; -.
DR   PRIDE; D3YYM0; -.
DR   Ensembl; ENSMUST00000189482; ENSMUSP00000140811; ENSMUSG00000100512.
DR   GeneID; 381867; -.
DR   KEGG; mmu:381867; -.
DR   UCSC; uc033iyh.1; mouse.
DR   CTD; 728361; -.
DR   MGI; MGI:2388075; Ovol3.
DR   VEuPathDB; HostDB:ENSMUSG00000100512; -.
DR   eggNOG; KOG3576; Eukaryota.
DR   GeneTree; ENSGT00940000162348; -.
DR   HOGENOM; CLU_087964_0_0_1; -.
DR   InParanoid; D3YYM0; -.
DR   OMA; NYAYRER; -.
DR   OrthoDB; 1419156at2759; -.
DR   PhylomeDB; D3YYM0; -.
DR   BioGRID-ORCS; 381867; 0 hits in 45 CRISPR screens.
DR   PRO; PR:D3YYM0; -.
DR   Proteomes; UP000000589; Chromosome 7.
DR   RNAct; D3YYM0; protein.
DR   Bgee; ENSMUSG00000100512; Expressed in primary oocyte and 12 other tissues.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR   GO; GO:0009913; P:epidermal cell differentiation; IBA:GO_Central.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR   InterPro; IPR027756; Ovo-like.
DR   InterPro; IPR036236; Znf_C2H2_sf.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   PANTHER; PTHR10032; PTHR10032; 1.
DR   Pfam; PF00096; zf-C2H2; 3.
DR   SMART; SM00355; ZnF_C2H2; 4.
DR   SUPFAM; SSF57667; SSF57667; 1.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 3.
DR   PROSITE; PS50157; ZINC_FINGER_C2H2_2; 3.
PE   3: Inferred from homology;
KW   Metal-binding; Nucleus; Reference proteome; Repeat; Zinc; Zinc-finger.
FT   CHAIN           1..189
FT                   /note="Putative transcription factor ovo-like protein 3"
FT                   /id="PRO_0000415414"
FT   ZN_FING         69..91
FT                   /note="C2H2-type 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         97..119
FT                   /note="C2H2-type 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         125..148
FT                   /note="C2H2-type 3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   REGION          1..20
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   189 AA;  21273 MW;  4D631B1C9949789D CRC64;
     MPRVFLVRSR RPQPPNWSHL PDQLRGDAYV PDCSSLAVPP AHRSSGLRDT WAVSSQGTLT
     SAPKGPGTLG CPLCPKAFPL QRMLTRHLKC HSPARRHVCH YCGKGFHDAF DLKRHMRTHT
     GIRPFRCGAC GKAFTQRCSL EAHLAKVHGQ PASYAYRERR EKLHVCEDCG FTSSRPDAYA
     QHRTLHRTT
 
 
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