OXA1L_ARATH
ID OXA1L_ARATH Reviewed; 431 AA.
AC Q9SKD3;
DT 14-NOV-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 125.
DE RecName: Full=Mitochondrial inner membrane protein OXA1-like;
DE Flags: Precursor;
GN Name=OXA1L; OrderedLocusNames=At2g46470; ORFNames=F11C10.16;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP IDENTIFICATION.
RC STRAIN=cv. Columbia;
RX PubMed=11148275; DOI=10.1093/pcp/pcd045;
RA Sakamoto W., Spielewoy N., Bonnard G., Murata M., Wintz H.;
RT "Mitochondrial localization of AtOXA1, an Arabidopsis homologue of yeast
RT Oxa1p involved in the insertion and assembly of protein complexes in
RT mitochondrial inner membrane.";
RL Plant Cell Physiol. 41:1157-1163(2000).
CC -!- FUNCTION: Probably required for the insertion of integral membrane
CC proteins into the mitochondrial inner membrane. May participate in the
CC activity and assembly of cytochrome oxidase (By similarity).
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
CC Multi-pass membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the OXA1/ALB3/YidC (TC 2.A.9.2) family.
CC {ECO:0000305}.
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DR EMBL; AC006526; AAD23047.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC10702.1; -; Genomic_DNA.
DR EMBL; AK117811; BAC42453.1; -; mRNA.
DR EMBL; AY080748; AAL85994.1; -; mRNA.
DR EMBL; BT000993; AAN41393.1; -; mRNA.
DR PIR; C84903; C84903.
DR RefSeq; NP_182170.1; NM_130211.5.
DR AlphaFoldDB; Q9SKD3; -.
DR SMR; Q9SKD3; -.
DR STRING; 3702.AT2G46470.1; -.
DR PaxDb; Q9SKD3; -.
DR PRIDE; Q9SKD3; -.
DR ProteomicsDB; 248679; -.
DR EnsemblPlants; AT2G46470.1; AT2G46470.1; AT2G46470.
DR GeneID; 819256; -.
DR Gramene; AT2G46470.1; AT2G46470.1; AT2G46470.
DR KEGG; ath:AT2G46470; -.
DR Araport; AT2G46470; -.
DR TAIR; locus:2039134; AT2G46470.
DR eggNOG; KOG1239; Eukaryota.
DR HOGENOM; CLU_029282_4_0_1; -.
DR InParanoid; Q9SKD3; -.
DR OMA; TVVKTHM; -.
DR OrthoDB; 1314061at2759; -.
DR PhylomeDB; Q9SKD3; -.
DR PRO; PR:Q9SKD3; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q9SKD3; baseline and differential.
DR Genevisible; Q9SKD3; AT.
DR GO; GO:0031305; C:integral component of mitochondrial inner membrane; IBA:GO_Central.
DR GO; GO:0032977; F:membrane insertase activity; IBA:GO_Central.
DR GO; GO:0051205; P:protein insertion into membrane; IBA:GO_Central.
DR GO; GO:0032979; P:protein insertion into mitochondrial inner membrane from matrix; IBA:GO_Central.
DR InterPro; IPR028055; Membr_insert_YidC/Oxa1_C.
DR InterPro; IPR001708; YidC/ALB3/OXA1/COX18.
DR PANTHER; PTHR12428; PTHR12428; 1.
DR Pfam; PF02096; 60KD_IMP; 1.
DR TIGRFAMs; TIGR03592; yidC_oxa1_cterm; 1.
PE 2: Evidence at transcript level;
KW Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome;
KW Transit peptide; Transmembrane; Transmembrane helix.
FT TRANSIT 1..22
FT /note="Mitochondrion"
FT /evidence="ECO:0000255"
FT CHAIN 23..431
FT /note="Mitochondrial inner membrane protein OXA1-like"
FT /id="PRO_0000020364"
FT TRANSMEM 119..139
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 155..175
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 227..247
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 269..289
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 312..332
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 362..414
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 389..414
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 431 AA; 47897 MW; A34BE2D0FD928401 CRC64;
MATCLRGITK RVNLLQRRVY PSCGHLIRDD RDETKSGSSD TMIREVLARN GTNKLSSMFA
DRHYQSFATG PLGLGLSSCR HMSSTPPEWS DKVDGIDFVA TEVVPDEIIE AVTTTSQAVV
PAINEVAIAA ADSAFPVAAL QHLIDAVHSF TGLNWWASIA LTTVLIRGVT IPILLNQLKA
TYKLNVLRPQ LEELRQEMST KAQDPEAMAE GQRRMQLLFK EHGVTPFTPL KGLIIQGPIF
ISFFFAIRNM AEKVPSFKTG GTLWFTDLTT TDTTYILPLL TAVTFLIMVE SNMQEGLEGN
PVAGTMKKFS RIIAFLSIPV LIGIEKALFC YWLTSNLFTL VYGLTLRRPD VRKLLNLPDV
VNSSTRQPSP SSPLPFSFAE PKDQSVVAQE KPPMSSESSS SVPDRRISRS SVLNQRIRTL
ERQLKDRKIK K
