ID   OXIR_STRLI              Reviewed;         297 AA.
AC   P35320;
DT   01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1994, sequence version 1.
DT   03-AUG-2022, entry version 67.
DE   RecName: Full=Probable oxidoreductase;
DE            EC=1.-.-.-;
OS   Streptomyces lividans.
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces.
OX   NCBI_TaxID=1916;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=66 / 1326; TRANSPOSON=Tn4811;
RX   PubMed=1332944; DOI=10.1128/jb.174.23.7762-7769.1992;
RA   Chen C.W., Yu T.-W., Chung H.-M., Chou C.-F.;
RT   "Discovery and characterization of a new transposable element, Tn4811, in
RT   Streptomyces lividans 66.";
RL   J. Bacteriol. 174:7762-7769(1992).
CC   -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC       family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; P35320; -.
DR   SMR; P35320; -.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020904; Sc_DH/Rdtase_CS.
DR   InterPro; IPR002347; SDR_fam.
DR   Pfam; PF00106; adh_short; 1.
DR   PRINTS; PR00081; GDHRDH.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   PROSITE; PS00061; ADH_SHORT; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase.
FT   CHAIN           1..297
FT                   /note="Probable oxidoreductase"
FT                   /id="PRO_0000054738"
FT   ACT_SITE        164
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU10001"
FT   BINDING         9..33
FT                   /ligand="NAD(+)"
FT                   /ligand_id="ChEBI:CHEBI:57540"
FT                   /evidence="ECO:0000250"
FT   BINDING         138
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   297 AA;  31248 MW;  9AFEC4A0E596EC32 CRC64;
     MDLTGRRAVV TGGASGLGAE TVRALAAAGA EVTIATRHPQ SAEPLVQEAA AAGAGRVHAE
     ALDLSDVASV DSFARAWRGP LDILVANAGI MALPTRTLTP YGWEMQLATN YLGHFALATG
     LHAALRDAGS ARIVVVSSGA HLGTPFDFED PHFARRPYDP WAAYGNSKTA DVLFTVGARR
     WAADGITANA LNPGYILTRL QRHVDDETMR AFGVMDDQGN VKPLPYYKTP EQGAATSVLL
     AASPLLNGVT GRYFEDNQEA RTVEDGDVQP GGVAAHALDP EAADRLWEYG ADTLSAG