ID   OXLD1_HUMAN             Reviewed;         147 AA.
AC   Q5BKU9; A6ND24;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   12-APR-2005, sequence version 1.
DT   03-AUG-2022, entry version 110.
DE   RecName: Full=Oxidoreductase-like domain-containing protein 1;
GN   Name=OXLD1; Synonyms=C17orf90;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16625196; DOI=10.1038/nature04689;
RA   Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R.,
RA   Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A.,
RA   Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J.,
RA   Chang J.L., Chen C.-K., Cook A., Corum B., Cuomo C.A., de Jong P.J.,
RA   DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R., Gnerre S.,
RA   Goldstein S., Grafham D.V., Grocock R., Hafez N., Hagopian D.S., Hart E.,
RA   Norman C.H., Humphray S., Jaffe D.B., Jones M., Kamal M., Khodiyar V.K.,
RA   LaButti K., Laird G., Lehoczky J., Liu X., Lokyitsang T., Loveland J.,
RA   Lui A., Macdonald P., Major J.E., Matthews L., Mauceli E., McCarroll S.A.,
RA   Mihalev A.H., Mudge J., Nguyen C., Nicol R., O'Leary S.B., Osoegawa K.,
RA   Schwartz D.C., Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D.,
RA   Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A.,
RA   Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C.;
RT   "DNA sequence of human chromosome 17 and analysis of rearrangement in the
RT   human lineage.";
RL   Nature 440:1045-1049(2006).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Placenta;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
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DR   EMBL; AC139530; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BC090923; AAH90923.1; -; mRNA.
DR   CCDS; CCDS32766.1; -.
DR   RefSeq; NP_001034931.1; NM_001039842.2.
DR   AlphaFoldDB; Q5BKU9; -.
DR   BioGRID; 130845; 59.
DR   IntAct; Q5BKU9; 37.
DR   STRING; 9606.ENSP00000363873; -.
DR   BioMuta; OXLD1; -.
DR   DMDM; 74736039; -.
DR   EPD; Q5BKU9; -.
DR   jPOST; Q5BKU9; -.
DR   MassIVE; Q5BKU9; -.
DR   MaxQB; Q5BKU9; -.
DR   PaxDb; Q5BKU9; -.
DR   PeptideAtlas; Q5BKU9; -.
DR   PRIDE; Q5BKU9; -.
DR   ProteomicsDB; 62700; -.
DR   Antibodypedia; 70942; 8 antibodies from 4 providers.
DR   DNASU; 339229; -.
DR   Ensembl; ENST00000374741.4; ENSP00000363873.3; ENSG00000204237.5.
DR   GeneID; 339229; -.
DR   KEGG; hsa:339229; -.
DR   MANE-Select; ENST00000374741.4; ENSP00000363873.3; NM_001039842.3; NP_001034931.1.
DR   UCSC; uc002kba.3; human.
DR   CTD; 339229; -.
DR   GeneCards; OXLD1; -.
DR   HGNC; HGNC:27901; OXLD1.
DR   HPA; ENSG00000204237; Low tissue specificity.
DR   neXtProt; NX_Q5BKU9; -.
DR   OpenTargets; ENSG00000204237; -.
DR   PharmGKB; PA162378543; -.
DR   VEuPathDB; HostDB:ENSG00000204237; -.
DR   eggNOG; ENOG502S74Z; Eukaryota.
DR   GeneTree; ENSGT00390000003596; -.
DR   HOGENOM; CLU_144239_0_0_1; -.
DR   InParanoid; Q5BKU9; -.
DR   OMA; RKFGKDH; -.
DR   OrthoDB; 1552217at2759; -.
DR   PhylomeDB; Q5BKU9; -.
DR   TreeFam; TF353117; -.
DR   PathwayCommons; Q5BKU9; -.
DR   SignaLink; Q5BKU9; -.
DR   BioGRID-ORCS; 339229; 21 hits in 1074 CRISPR screens.
DR   ChiTaRS; OXLD1; human.
DR   GenomeRNAi; 339229; -.
DR   Pharos; Q5BKU9; Tdark.
DR   PRO; PR:Q5BKU9; -.
DR   Proteomes; UP000005640; Chromosome 17.
DR   RNAct; Q5BKU9; protein.
DR   Bgee; ENSG00000204237; Expressed in mucosa of transverse colon and 181 other tissues.
DR   ExpressionAtlas; Q5BKU9; baseline and differential.
DR   Genevisible; Q5BKU9; HS.
DR   InterPro; IPR019180; Oxidoreductase-like_N.
DR   InterPro; IPR039251; OXLD1.
DR   PANTHER; PTHR21193; PTHR21193; 1.
DR   Pfam; PF09791; Oxidored-like; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           1..147
FT                   /note="Oxidoreductase-like domain-containing protein 1"
FT                   /id="PRO_0000314123"
FT   DOMAIN          81..108
FT                   /note="Oxidoreductase-like"
FT   REGION          36..82
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        18
FT                   /note="R -> L (in Ref. 1; AC139530)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   147 AA;  15855 MW;  DFDD7FD34D5FF176 CRC64;
     MLLRRVVEGG RAVAAAVRGS GARRFSSPDC CQRLPGGGSF LQRHHPGAQA PDGRRKFGTD
     HVEVGSQAGA DGTRPPKASL PPELQPPTNC CMSGCPNCVW VEYADRLLQH FQDGGERALA
     ALEEHVADEN LKAFLRMEIR LHTRCGG