OXLD1_MOUSE
ID OXLD1_MOUSE Reviewed; 201 AA.
AC Q9CR10;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 110.
DE RecName: Full=Oxidoreductase-like domain-containing protein 1;
GN Name=Oxld1;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Corpus striatum, and Pancreas;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J;
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [3]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Heart, Kidney, and Liver;
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
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DR EMBL; AK007842; BAB25299.1; -; mRNA.
DR EMBL; AK021150; BAB32307.1; -; mRNA.
DR EMBL; AL669855; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR CCDS; CCDS25735.1; -.
DR RefSeq; NP_079836.1; NM_025560.2.
DR AlphaFoldDB; Q9CR10; -.
DR STRING; 10090.ENSMUSP00000036860; -.
DR MaxQB; Q9CR10; -.
DR PaxDb; Q9CR10; -.
DR PRIDE; Q9CR10; -.
DR ProteomicsDB; 295494; -.
DR Antibodypedia; 70942; 8 antibodies from 4 providers.
DR Ensembl; ENSMUST00000044007; ENSMUSP00000036860; ENSMUSG00000039670.
DR GeneID; 66431; -.
DR KEGG; mmu:66431; -.
DR UCSC; uc007mst.1; mouse.
DR CTD; 339229; -.
DR MGI; MGI:1913681; Oxld1.
DR VEuPathDB; HostDB:ENSMUSG00000039670; -.
DR eggNOG; ENOG502S8KH; Eukaryota.
DR GeneTree; ENSGT00390000003596; -.
DR HOGENOM; CLU_117694_0_0_1; -.
DR InParanoid; Q9CR10; -.
DR OMA; RKFGKDH; -.
DR OrthoDB; 1552217at2759; -.
DR PhylomeDB; Q9CR10; -.
DR TreeFam; TF353117; -.
DR BioGRID-ORCS; 66431; 4 hits in 74 CRISPR screens.
DR PRO; PR:Q9CR10; -.
DR Proteomes; UP000000589; Chromosome 11.
DR RNAct; Q9CR10; protein.
DR Bgee; ENSMUSG00000039670; Expressed in right kidney and 177 other tissues.
DR ExpressionAtlas; Q9CR10; baseline and differential.
DR Genevisible; Q9CR10; MM.
DR GO; GO:0005739; C:mitochondrion; HDA:MGI.
DR InterPro; IPR019180; Oxidoreductase-like_N.
DR InterPro; IPR039251; OXLD1.
DR PANTHER; PTHR21193; PTHR21193; 1.
DR Pfam; PF09791; Oxidored-like; 1.
PE 1: Evidence at protein level;
KW Reference proteome.
FT CHAIN 1..201
FT /note="Oxidoreductase-like domain-containing protein 1"
FT /id="PRO_0000314124"
FT DOMAIN 134..161
FT /note="Oxidoreductase-like"
FT REGION 102..134
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 102..121
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 201 AA; 22178 MW; 35561E5021204CF3 CRC64;
MGSPLQTLSR GGRVRAALWC WTQARGLSGR QCPNRVARSL SCSRGFPVRG GRPALGGTMV
SVLTESFLQG TQHFSSWDCC QSLHRHRAPV QVTDSRRNLG MDHREEGFQV GTEDDREPKA
SLPRGNPTGP PCSLPPELEP PTNCCMSGCP NCVWVDYAEA LLRLYQDGGE KALAILEEHV
TDENLKAFLR MEIRLRMQSG A
