ID   OXND1_BOVIN             Reviewed;         309 AA.
AC   Q58DM7;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   26-APR-2005, sequence version 1.
DT   03-AUG-2022, entry version 84.
DE   RecName: Full=Oxidoreductase NAD-binding domain-containing protein 1;
DE            EC=1.-.-.-;
DE   Flags: Precursor;
GN   Name=OXNAD1;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX   PubMed=16305752; DOI=10.1186/1471-2164-6-166;
RA   Harhay G.P., Sonstegard T.S., Keele J.W., Heaton M.P., Clawson M.L.,
RA   Snelling W.M., Wiedmann R.T., Van Tassell C.P., Smith T.P.L.;
RT   "Characterization of 954 bovine full-CDS cDNA sequences.";
RL   BMC Genomics 6:166-166(2005).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BT021570; AAX46417.1; -; mRNA.
DR   RefSeq; NP_001030262.1; NM_001035090.1.
DR   RefSeq; XP_010800047.1; XM_010801745.2.
DR   AlphaFoldDB; Q58DM7; -.
DR   SMR; Q58DM7; -.
DR   STRING; 9913.ENSBTAP00000006434; -.
DR   PaxDb; Q58DM7; -.
DR   PRIDE; Q58DM7; -.
DR   Ensembl; ENSBTAT00000006434; ENSBTAP00000006434; ENSBTAG00000004891.
DR   GeneID; 510462; -.
DR   KEGG; bta:510462; -.
DR   CTD; 92106; -.
DR   VEuPathDB; HostDB:ENSBTAG00000004891; -.
DR   VGNC; VGNC:32512; OXNAD1.
DR   eggNOG; KOG0534; Eukaryota.
DR   GeneTree; ENSGT00390000004280; -.
DR   HOGENOM; CLU_003827_7_1_1; -.
DR   InParanoid; Q58DM7; -.
DR   OMA; WIDFFIP; -.
DR   OrthoDB; 696109at2759; -.
DR   TreeFam; TF329774; -.
DR   Proteomes; UP000009136; Chromosome 1.
DR   Bgee; ENSBTAG00000004891; Expressed in thyroid gland and 106 other tissues.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.80; -; 1.
DR   InterPro; IPR017927; FAD-bd_FR_type.
DR   InterPro; IPR039261; FNR_nucleotide-bd.
DR   InterPro; IPR001433; OxRdtase_FAD/NAD-bd.
DR   InterPro; IPR017938; Riboflavin_synthase-like_b-brl.
DR   Pfam; PF00175; NAD_binding_1; 1.
DR   SUPFAM; SSF52343; SSF52343; 1.
DR   SUPFAM; SSF63380; SSF63380; 1.
DR   PROSITE; PS51384; FAD_FR; 1.
PE   2: Evidence at transcript level;
KW   NAD; Oxidoreductase; Reference proteome; Signal.
FT   SIGNAL          1..14
FT                   /evidence="ECO:0000255"
FT   CHAIN           15..309
FT                   /note="Oxidoreductase NAD-binding domain-containing protein
FT                   1"
FT                   /id="PRO_0000299570"
FT   DOMAIN          47..161
FT                   /note="FAD-binding FR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00716"
FT   BINDING         175..180
FT                   /ligand="NAD(+)"
FT                   /ligand_id="ChEBI:CHEBI:57540"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   309 AA;  34597 MW;  C7AA1DD0BE6EB418 CRC64;
     MVVVIPRLLR GSLGAICTQA ALLRSTPSAF RYLTRSSVMK SKRRPDHLER TADVVRQEVV
     SAAKVCGVAS ESPSVKRLCL LVADKDFSFK AGQWVDFFIP GVSVVGGFSI CSSPRLLEQE
     RMIELAVKHA NHPPALWIHN QCTLDSEVAV RVGGEFFFDP KPTDASRNLV LIAGGVGINP
     LLSILRHAAD LLRERASKGQ GYEMGTVRLL YSAKDTSELL FKKNILDLVN EFPEKIACSL
     HVTKQTTQIT ADLRPYITEG RITQKEIRDH ISKETLFYIC GPPPMTDFFS KELESSRVPR
     EHICFEKWW