ID   OXND1_XENLA             Reviewed;         314 AA.
AC   Q7T0X7;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2003, sequence version 1.
DT   03-AUG-2022, entry version 68.
DE   RecName: Full=Oxidoreductase NAD-binding domain-containing protein 1;
DE            EC=1.-.-.-;
DE   Flags: Precursor;
GN   Name=oxnad1;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BC055995; AAH55995.1; -; mRNA.
DR   EMBL; BC106287; AAI06288.1; -; mRNA.
DR   RefSeq; NP_001079844.1; NM_001086375.1.
DR   AlphaFoldDB; Q7T0X7; -.
DR   SMR; Q7T0X7; -.
DR   DNASU; 379534; -.
DR   GeneID; 379534; -.
DR   KEGG; xla:379534; -.
DR   CTD; 379534; -.
DR   Xenbase; XB-GENE-971240; oxnad1.L.
DR   OrthoDB; 696109at2759; -.
DR   Proteomes; UP000186698; Chromosome 6L.
DR   Bgee; 379534; Expressed in oocyte and 20 other tissues.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.80; -; 1.
DR   InterPro; IPR017927; FAD-bd_FR_type.
DR   InterPro; IPR039261; FNR_nucleotide-bd.
DR   InterPro; IPR001433; OxRdtase_FAD/NAD-bd.
DR   InterPro; IPR017938; Riboflavin_synthase-like_b-brl.
DR   Pfam; PF00175; NAD_binding_1; 1.
DR   SUPFAM; SSF52343; SSF52343; 1.
DR   SUPFAM; SSF63380; SSF63380; 1.
DR   PROSITE; PS51384; FAD_FR; 1.
PE   2: Evidence at transcript level;
KW   NAD; Oxidoreductase; Reference proteome; Signal.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000255"
FT   CHAIN           19..314
FT                   /note="Oxidoreductase NAD-binding domain-containing protein
FT                   1"
FT                   /id="PRO_0000299575"
FT   DOMAIN          63..166
FT                   /note="FAD-binding FR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00716"
FT   BINDING         180..185
FT                   /ligand="NAD(+)"
FT                   /ligand_id="ChEBI:CHEBI:57540"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   314 AA;  34692 MW;  842904387EC7F777 CRC64;
     MALVAGSAAY QVLRGVTGTF PTQSATLLAR APALCAHTMN RRRMSSSQQT DHLERTANTF
     RQEIISPAKV CGITNESATV KRVRLAIANR EFTFKAGQWV DFFIPGVPKV GGFSICSSPG
     LLETEGVLEL AVKYNLHPPA HWIHSQCALG SEVAIRVGGE FCFDPQPSDL PLDLVLIAGG
     VGINPLFSIL LHVADLHKTR EITGRGFQMG NVKLYYCAKN TGELLFKRNI LDLVNSFPGK
     VTCSFHVTQQ SSPICRELQP FITEGRITEK DLASYVSTDQ LCYICGPPPM IESMCKQLQS
     LHLPKERILF EKWW