ID   OXND1_XENTR             Reviewed;         314 AA.
AC   A4IHY0;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2007, sequence version 1.
DT   03-AUG-2022, entry version 69.
DE   RecName: Full=Oxidoreductase NAD-binding domain-containing protein 1;
DE            EC=1.-.-.-;
DE   Flags: Precursor;
GN   Name=oxnad1;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; BC135746; AAI35747.1; -; mRNA.
DR   RefSeq; NP_001096328.1; NM_001102858.1.
DR   AlphaFoldDB; A4IHY0; -.
DR   SMR; A4IHY0; -.
DR   STRING; 8364.ENSXETP00000054711; -.
DR   PaxDb; A4IHY0; -.
DR   DNASU; 100124914; -.
DR   GeneID; 100124914; -.
DR   KEGG; xtr:100124914; -.
DR   CTD; 92106; -.
DR   Xenbase; XB-GENE-971236; oxnad1.
DR   eggNOG; KOG0534; Eukaryota.
DR   HOGENOM; CLU_003827_7_1_1; -.
DR   InParanoid; A4IHY0; -.
DR   OMA; HQDRTAN; -.
DR   OrthoDB; 696109at2759; -.
DR   TreeFam; TF329774; -.
DR   Proteomes; UP000008143; Chromosome 6.
DR   Proteomes; UP000790000; Unplaced.
DR   ExpressionAtlas; A4IHY0; differential.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.80; -; 1.
DR   InterPro; IPR017927; FAD-bd_FR_type.
DR   InterPro; IPR039261; FNR_nucleotide-bd.
DR   InterPro; IPR001433; OxRdtase_FAD/NAD-bd.
DR   InterPro; IPR017938; Riboflavin_synthase-like_b-brl.
DR   Pfam; PF00175; NAD_binding_1; 1.
DR   SUPFAM; SSF52343; SSF52343; 1.
DR   SUPFAM; SSF63380; SSF63380; 1.
DR   PROSITE; PS51384; FAD_FR; 1.
PE   2: Evidence at transcript level;
KW   NAD; Oxidoreductase; Reference proteome; Signal.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000255"
FT   CHAIN           19..314
FT                   /note="Oxidoreductase NAD-binding domain-containing protein
FT                   1"
FT                   /id="PRO_0000299576"
FT   DOMAIN          63..166
FT                   /note="FAD-binding FR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00716"
FT   BINDING         180..185
FT                   /ligand="NAD(+)"
FT                   /ligand_id="ChEBI:CHEBI:57540"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   314 AA;  34779 MW;  876C85F1EFA44789 CRC64;
     MALVAGSAAY QVLRGVTGTF PTQSATLLAR APALCARTLN RRRMSSRRQT DHLERTANTF
     RQEIISPAKV CEITNESATV KRVRLAIANR EFTFKAGQWV DFFIPGVPKV GGFSICSCPG
     LLETEGVLEL AVKYNLHPPA HWIHSQCTLG SEVAVRVGGE FCFDPQPSDL PLDLVLIAGG
     VGINPLFSIL LHVADLHKTH EMTGRGFQMG NVKLYYCAKN TGELLFKRNI LDLVKSFPGK
     ITCSFHVTQQ SSPVCVELQP FITEGRITEK DLASYVSTDQ LCYICGPPPM IESTCKQLES
     LHVPKEQILF EKWW