ID   OXR1_ASPFU              Reviewed;         324 AA.
AC   Q4WX99;
DT   06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2005, sequence version 1.
DT   25-MAY-2022, entry version 79.
DE   RecName: Full=Oxidation resistance protein 1;
GN   Name=oxr1; ORFNames=AFUA_3G08740;
OS   Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC
OS   A1100) (Aspergillus fumigatus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Fumigati.
OX   NCBI_TaxID=330879;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100;
RX   PubMed=16372009; DOI=10.1038/nature04332;
RA   Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J.,
RA   Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J.W., Bowyer P.,
RA   Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.L.,
RA   Fedorova N., Fedorova N.D., Feldblyum T.V., Fischer R., Fosker N.,
RA   Fraser A., Garcia J.L., Garcia M.J., Goble A., Goldman G.H., Gomi K.,
RA   Griffith-Jones S., Gwilliam R., Haas B.J., Haas H., Harris D.E.,
RA   Horiuchi H., Huang J., Humphray S., Jimenez J., Keller N., Khouri H.,
RA   Kitamoto K., Kobayashi T., Konzack S., Kulkarni R., Kumagai T., Lafton A.,
RA   Latge J.-P., Li W., Lord A., Lu C., Majoros W.H., May G.S., Miller B.L.,
RA   Mohamoud Y., Molina M., Monod M., Mouyna I., Mulligan S., Murphy L.D.,
RA   O'Neil S., Paulsen I., Penalva M.A., Pertea M., Price C., Pritchard B.L.,
RA   Quail M.A., Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U.,
RA   Renauld H., Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M.,
RA   Ronning C.M., Rutter S., Salzberg S.L., Sanchez M., Sanchez-Ferrero J.C.,
RA   Saunders D., Seeger K., Squares R., Squares S., Takeuchi M., Tekaia F.,
RA   Turner G., Vazquez de Aldana C.R., Weidman J., White O., Woodward J.R.,
RA   Yu J.-H., Fraser C.M., Galagan J.E., Asai K., Machida M., Hall N.,
RA   Barrell B.G., Denning D.W.;
RT   "Genomic sequence of the pathogenic and allergenic filamentous fungus
RT   Aspergillus fumigatus.";
RL   Nature 438:1151-1156(2005).
CC   -!- FUNCTION: May be involved in protection from oxidative damage.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the OXR1 family. {ECO:0000305}.
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DR   EMBL; AAHF01000002; EAL92704.1; -; Genomic_DNA.
DR   RefSeq; XP_754742.1; XM_749649.1.
DR   AlphaFoldDB; Q4WX99; -.
DR   SMR; Q4WX99; -.
DR   STRING; 746128.CADAFUBP00003953; -.
DR   EnsemblFungi; EAL92704; EAL92704; AFUA_3G08740.
DR   GeneID; 3512145; -.
DR   KEGG; afm:AFUA_3G08740; -.
DR   eggNOG; KOG2372; Eukaryota.
DR   HOGENOM; CLU_029204_0_1_1; -.
DR   InParanoid; Q4WX99; -.
DR   OMA; ASYFSYP; -.
DR   OrthoDB; 767847at2759; -.
DR   Proteomes; UP000002530; Chromosome 3.
DR   GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0006979; P:response to oxidative stress; IBA:GO_Central.
DR   InterPro; IPR006571; TLDc_dom.
DR   Pfam; PF07534; TLD; 1.
DR   SMART; SM00584; TLDc; 1.
DR   PROSITE; PS51886; TLDC; 1.
PE   3: Inferred from homology;
KW   Mitochondrion; Reference proteome.
FT   CHAIN           1..324
FT                   /note="Oxidation resistance protein 1"
FT                   /id="PRO_0000058110"
FT   DOMAIN          124..324
FT                   /note="TLDc"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01234"
FT   REGION          1..35
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          63..113
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          244..292
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        77..96
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   324 AA;  34581 MW;  3E7533D3F1E7CBDD CRC64;
     MSSLSQGDSP SLTATASSSS SSSTSGSRTP KANNSFNQSA ASYFSYPVTH VVSGLYRRLT
     EPNITKASRK DSNSPNRKMN ARNNRDSSTT SPDIFVPIRT ASPFQPPPLT PLTLTPGPGV
     PQQQLLTRAL AEEIRLLVPA RLQLVDTWRL AYSLDRDGAS LSTLYEHCRD FSHRSPRAGY
     VLIVRDSSPA GAVFGAYMTD PPHPDSHYFG TGECFLWRAS VLPSPSNLLN INGPQSEEML
     ERAGLPLPPS ADTTHAGRST TLRGDSRGHG DGRLAAPRAN GGTGAGAASG ASTPERIRFK
     AFPYSGVNDY MMFCETGFLS LGGG