OXR1_GIBZE
ID OXR1_GIBZE Reviewed; 326 AA.
AC Q4I8S2; A0A0E0SPB0; V6RER0;
DT 06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT 16-AUG-2005, sequence version 1.
DT 25-MAY-2022, entry version 74.
DE RecName: Full=Oxidation resistance protein 1;
GN Name=OXR1; ORFNames=FGRRES_06386, FGSG_06386;
OS Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084
OS / PH-1) (Wheat head blight fungus) (Fusarium graminearum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium.
OX NCBI_TaxID=229533;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1;
RX PubMed=17823352; DOI=10.1126/science.1143708;
RA Cuomo C.A., Gueldener U., Xu J.-R., Trail F., Turgeon B.G., Di Pietro A.,
RA Walton J.D., Ma L.-J., Baker S.E., Rep M., Adam G., Antoniw J., Baldwin T.,
RA Calvo S.E., Chang Y.-L., DeCaprio D., Gale L.R., Gnerre S., Goswami R.S.,
RA Hammond-Kosack K., Harris L.J., Hilburn K., Kennell J.C., Kroken S.,
RA Magnuson J.K., Mannhaupt G., Mauceli E.W., Mewes H.-W., Mitterbauer R.,
RA Muehlbauer G., Muensterkoetter M., Nelson D., O'Donnell K., Ouellet T.,
RA Qi W., Quesneville H., Roncero M.I.G., Seong K.-Y., Tetko I.V., Urban M.,
RA Waalwijk C., Ward T.J., Yao J., Birren B.W., Kistler H.C.;
RT "The Fusarium graminearum genome reveals a link between localized
RT polymorphism and pathogen specialization.";
RL Science 317:1400-1402(2007).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1;
RX PubMed=20237561; DOI=10.1038/nature08850;
RA Ma L.-J., van der Does H.C., Borkovich K.A., Coleman J.J., Daboussi M.-J.,
RA Di Pietro A., Dufresne M., Freitag M., Grabherr M., Henrissat B.,
RA Houterman P.M., Kang S., Shim W.-B., Woloshuk C., Xie X., Xu J.-R.,
RA Antoniw J., Baker S.E., Bluhm B.H., Breakspear A., Brown D.W.,
RA Butchko R.A.E., Chapman S., Coulson R., Coutinho P.M., Danchin E.G.J.,
RA Diener A., Gale L.R., Gardiner D.M., Goff S., Hammond-Kosack K.E.,
RA Hilburn K., Hua-Van A., Jonkers W., Kazan K., Kodira C.D., Koehrsen M.,
RA Kumar L., Lee Y.-H., Li L., Manners J.M., Miranda-Saavedra D.,
RA Mukherjee M., Park G., Park J., Park S.-Y., Proctor R.H., Regev A.,
RA Ruiz-Roldan M.C., Sain D., Sakthikumar S., Sykes S., Schwartz D.C.,
RA Turgeon B.G., Wapinski I., Yoder O., Young S., Zeng Q., Zhou S.,
RA Galagan J., Cuomo C.A., Kistler H.C., Rep M.;
RT "Comparative genomics reveals mobile pathogenicity chromosomes in
RT Fusarium.";
RL Nature 464:367-373(2010).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1;
RX PubMed=26198851; DOI=10.1186/s12864-015-1756-1;
RA King R., Urban M., Hammond-Kosack M.C.U., Hassani-Pak K.,
RA Hammond-Kosack K.E.;
RT "The completed genome sequence of the pathogenic ascomycete fungus Fusarium
RT graminearum.";
RL BMC Genomics 16:544-544(2015).
CC -!- FUNCTION: May be involved in protection from oxidative damage.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the OXR1 family. {ECO:0000305}.
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DR EMBL; DS231665; ESU12472.1; -; Genomic_DNA.
DR EMBL; HG970334; CEF88273.1; -; Genomic_DNA.
DR RefSeq; XP_011325048.1; XM_011326746.1.
DR AlphaFoldDB; Q4I8S2; -.
DR SMR; Q4I8S2; -.
DR STRING; 5518.FGSG_06386P0; -.
DR EnsemblFungi; ESU12472; ESU12472; FGSG_06386.
DR GeneID; 23553519; -.
DR KEGG; fgr:FGSG_06386; -.
DR VEuPathDB; FungiDB:FGRAMPH1_01G20185; -.
DR eggNOG; KOG2372; Eukaryota.
DR HOGENOM; CLU_029204_0_1_1; -.
DR InParanoid; Q4I8S2; -.
DR Proteomes; UP000070720; Chromosome 3.
DR GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR InterPro; IPR006571; TLDc_dom.
DR Pfam; PF07534; TLD; 2.
DR SMART; SM00584; TLDc; 1.
DR PROSITE; PS51886; TLDC; 1.
PE 3: Inferred from homology;
KW Mitochondrion; Reference proteome.
FT CHAIN 1..326
FT /note="Oxidation resistance protein 1"
FT /id="PRO_0000058116"
FT DOMAIN 111..325
FT /note="TLDc"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01234"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 209..249
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 215..230
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 326 AA; 35404 MW; 6416414C1A5DC49F CRC64;
MSFSDRNDSP ETPESSGTGT PVNSNRASAS YITNMWTGLI RRFSSEGSFP SQADTAYDDN
FNYHDGNGHN TKDGINGVFS PVRRTASPMR PPPLDPLILH GYRQGTPSSA KLLSAAVAEE
IRTMVPERLR IVDDWNLIYS LEQDGASLAT LYQRCRQFEG KRAGFVLVVK DLEGGVFGAY
LSEYPHPAHT YFGNGECFLW RASNITPLPP PPSADTTNLN SRNTTLAPPP PSSEANTPTH
SRPASPTPSE AVRFKAFPYS GLNDFCINCE TGFLSVGSGG GHYGLWLDNG LEVGHSSRCE
TYGNEPLSDE GTKFGVIGVE LWVMGV