ID   OXR1_KLULA              Reviewed;         250 AA.
AC   Q6CMK8;
DT   06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 75.
DE   RecName: Full=Oxidation resistance protein 1;
GN   Name=OXR1; OrderedLocusNames=KLLA0E19547g;
OS   Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 /
OS   NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX   NCBI_TaxID=284590;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: May be involved in protection from oxidative damage.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the OXR1 family. {ECO:0000305}.
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DR   EMBL; CR382125; CAG99918.1; -; Genomic_DNA.
DR   RefSeq; XP_454831.1; XM_454831.1.
DR   AlphaFoldDB; Q6CMK8; -.
DR   SMR; Q6CMK8; -.
DR   STRING; 28985.XP_454831.1; -.
DR   EnsemblFungi; CAG99918; CAG99918; KLLA0_E19449g.
DR   GeneID; 2893962; -.
DR   KEGG; kla:KLLA0_E19449g; -.
DR   eggNOG; KOG2372; Eukaryota.
DR   HOGENOM; CLU_029204_0_0_1; -.
DR   InParanoid; Q6CMK8; -.
DR   OMA; YRGGSHP; -.
DR   Proteomes; UP000000598; Chromosome E.
DR   GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR   GO; GO:0034599; P:cellular response to oxidative stress; IEA:EnsemblFungi.
DR   InterPro; IPR006571; TLDc_dom.
DR   Pfam; PF07534; TLD; 1.
DR   SMART; SM00584; TLDc; 1.
DR   PROSITE; PS51886; TLDC; 1.
PE   3: Inferred from homology;
KW   Mitochondrion; Reference proteome.
FT   CHAIN           1..250
FT                   /note="Oxidation resistance protein 1"
FT                   /id="PRO_0000058117"
FT   DOMAIN          61..250
FT                   /note="TLDc"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01234"
SQ   SEQUENCE   250 AA;  28723 MW;  8AB626CC47E834CA CRC64;
     MSGFRNRIQS WGKGLGTVLS DSIGDESSEK TSRSIQHNHY EEDDALPPVH LIGYSEKTKN
     RLLSKEMCEE LRQLMPTRIQ LYTEWTLLYS LEQHGASLHS LYDKLKYDTN NNARVGYVIV
     IRDRKGGIFG GYANETFHPT DSRRYYGNGE CFLWKMEKVP DLQLHDKHDC KQDSHNWQLR
     GFPYTGENEF SIYCTSTFLS MGAGDGHYGL WIDDGLFRGV TFPSMTFGND ILSREGSKFH
     IVGVEVWRVG