ID   OXYA_SCYCA              Reviewed;           9 AA.
AC   P42996;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   07-OCT-2020, entry version 47.
DE   RecName: Full=Asvatocin;
OS   Scyliorhinus canicula (Small-spotted catshark) (Squalus canicula).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC   Elasmobranchii; Galeomorphii; Galeoidea; Carcharhiniformes; Scyliorhinidae;
OC   Scyliorhinus.
OX   NCBI_TaxID=7830;
RN   [1]
RP   PROTEIN SEQUENCE, AND AMIDATION AT GLY-9.
RC   TISSUE=Pituitary;
RX   PubMed=7972045; DOI=10.1073/pnas.91.23.11266;
RA   Chauvet J., Rouille Y., Chauveau C., Chauvet M.-T., Acher R.;
RT   "Special evolution of neurohypophysial hormones in cartilaginous fishes:
RT   asvatocin and phasvatocin, two oxytocin-like peptides isolated from the
RT   spotted dogfish (Scyliorhinus caniculus).";
RL   Proc. Natl. Acad. Sci. U.S.A. 91:11266-11270(1994).
CC   -!- FUNCTION: Displays oxytocic activity on rat uterus.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- SIMILARITY: Belongs to the vasopressin/oxytocin family. {ECO:0000305}.
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DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005185; F:neurohypophyseal hormone activity; IEA:InterPro.
DR   InterPro; IPR022423; Neurohypophysial_hormone_CS.
DR   PROSITE; PS00264; NEUROHYPOPHYS_HORM; 1.
PE   1: Evidence at protein level;
KW   Amidation; Direct protein sequencing; Disulfide bond; Hormone; Secreted.
FT   PEPTIDE         1..9
FT                   /note="Asvatocin"
FT                   /id="PRO_0000044092"
FT   MOD_RES         9
FT                   /note="Glycine amide"
FT                   /evidence="ECO:0000269|PubMed:7972045"
FT   DISULFID        1..6
SQ   SEQUENCE   9 AA;  982 MW;  17EDD76EB444404B CRC64;
     CYINNCPVG