OXYA_SQUAC
ID OXYA_SQUAC Reviewed; 9 AA.
AC P42999;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1995, sequence version 1.
DT 26-FEB-2020, entry version 49.
DE RecName: Full=Aspartocin;
DE AltName: Full=Aspargtocin;
OS Squalus acanthias (Spiny dogfish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC Elasmobranchii; Squalomorphii; Squaliformes; Squalidae; Squalus.
OX NCBI_TaxID=7797;
RN [1]
RP PROTEIN SEQUENCE.
RX PubMed=5083097; DOI=10.1111/j.1432-1033.1972.tb01951.x;
RA Acher R., Chauvet J., Chauvet M.-T.;
RT "Phylogeny of the neurohypophysial hormones. Two new active peptides
RT isolated from a cartilaginous fish, Squalus acanthias.";
RL Eur. J. Biochem. 29:12-19(1972).
RN [2]
RP PROTEIN SEQUENCE, AND AMIDATION AT GLY-9.
RX PubMed=4622083;
RA Acher R., Chauvet J., Chauvet M.-T., Fontaine M.;
RT "Identification of 2 new neurohypophyseal hormones, valitocin (Val8-
RT oxytocin) and aspartocin (Asn4-oxytocin) in a selachian fish, the spiny
RT dog-fish (Squalus acanthias).";
RL C. R. Hebd. Seances Acad. Sci., D, Sci. Nat. 274:313-316(1972).
CC -!- SUBCELLULAR LOCATION: Secreted.
CC -!- SIMILARITY: Belongs to the vasopressin/oxytocin family. {ECO:0000305}.
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DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0005185; F:neurohypophyseal hormone activity; IEA:InterPro.
DR InterPro; IPR022423; Neurohypophysial_hormone_CS.
DR Pfam; PF00220; Hormone_4; 1.
DR PROSITE; PS00264; NEUROHYPOPHYS_HORM; 1.
PE 1: Evidence at protein level;
KW Amidation; Direct protein sequencing; Disulfide bond; Hormone; Secreted.
FT PEPTIDE 1..9
FT /note="Aspartocin"
FT /id="PRO_0000044094"
FT MOD_RES 9
FT /note="Glycine amide"
FT /evidence="ECO:0000269|PubMed:4622083"
FT DISULFID 1..6
SQ SEQUENCE 9 AA; 996 MW; 17F8376EB444404B CRC64;
CYINNCPLG