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OXYA_SQUAC
ID   OXYA_SQUAC              Reviewed;           9 AA.
AC   P42999;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   26-FEB-2020, entry version 49.
DE   RecName: Full=Aspartocin;
DE   AltName: Full=Aspargtocin;
OS   Squalus acanthias (Spiny dogfish).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC   Elasmobranchii; Squalomorphii; Squaliformes; Squalidae; Squalus.
OX   NCBI_TaxID=7797;
RN   [1]
RP   PROTEIN SEQUENCE.
RX   PubMed=5083097; DOI=10.1111/j.1432-1033.1972.tb01951.x;
RA   Acher R., Chauvet J., Chauvet M.-T.;
RT   "Phylogeny of the neurohypophysial hormones. Two new active peptides
RT   isolated from a cartilaginous fish, Squalus acanthias.";
RL   Eur. J. Biochem. 29:12-19(1972).
RN   [2]
RP   PROTEIN SEQUENCE, AND AMIDATION AT GLY-9.
RX   PubMed=4622083;
RA   Acher R., Chauvet J., Chauvet M.-T., Fontaine M.;
RT   "Identification of 2 new neurohypophyseal hormones, valitocin (Val8-
RT   oxytocin) and aspartocin (Asn4-oxytocin) in a selachian fish, the spiny
RT   dog-fish (Squalus acanthias).";
RL   C. R. Hebd. Seances Acad. Sci., D, Sci. Nat. 274:313-316(1972).
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- SIMILARITY: Belongs to the vasopressin/oxytocin family. {ECO:0000305}.
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DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005185; F:neurohypophyseal hormone activity; IEA:InterPro.
DR   InterPro; IPR022423; Neurohypophysial_hormone_CS.
DR   Pfam; PF00220; Hormone_4; 1.
DR   PROSITE; PS00264; NEUROHYPOPHYS_HORM; 1.
PE   1: Evidence at protein level;
KW   Amidation; Direct protein sequencing; Disulfide bond; Hormone; Secreted.
FT   PEPTIDE         1..9
FT                   /note="Aspartocin"
FT                   /id="PRO_0000044094"
FT   MOD_RES         9
FT                   /note="Glycine amide"
FT                   /evidence="ECO:0000269|PubMed:4622083"
FT   DISULFID        1..6
SQ   SEQUENCE   9 AA;  996 MW;  17F8376EB444404B CRC64;
     CYINNCPLG
 
 
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