ID   OXYR_DICCH              Reviewed;         305 AA.
AC   Q9X725;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1999, sequence version 1.
DT   25-MAY-2022, entry version 71.
DE   RecName: Full=Hydrogen peroxide-inducible genes activator;
GN   Name=oxyR;
OS   Dickeya chrysanthemi (Pectobacterium chrysanthemi) (Erwinia chrysanthemi).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Pectobacteriaceae; Dickeya.
OX   NCBI_TaxID=556;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=EC16;
RA   Miguel E., Poza-Carrion C., Lopez-Solanilla E., Garcia-Olmedo F.,
RA   Rodriguez-Palenzuela P.;
RT   "OxyR mutants of Erwinia chrysanthemi are hypersensitive to H2O2 but retain
RT   full virulence in potato tuber.";
RL   Submitted (APR-1998) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for the induction of a regulon of hydrogen peroxide
CC       inducible genes such as catalase and glutathione-reductase.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000305}.
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DR   EMBL; AJ005255; CAB40388.1; -; Genomic_DNA.
DR   RefSeq; WP_039999062.1; NZ_JAFCAF010000005.1.
DR   AlphaFoldDB; Q9X725; -.
DR   SMR; Q9X725; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   PRINTS; PR00039; HTHLYSR.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
KW   Activator; DNA-binding; Transcription; Transcription regulation.
FT   CHAIN           1..305
FT                   /note="Hydrogen peroxide-inducible genes activator"
FT                   /id="PRO_0000105732"
FT   DOMAIN          1..58
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
FT   DNA_BIND        18..37
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
SQ   SEQUENCE   305 AA;  34348 MW;  51F1AA9DAE634304 CRC64;
     MNIRDLEYLV ALAEHRHFRR AADSCHVSQP TLSGQIRKLE DELGVMLLER TSRKVLFTQA
     GLLLVEQART VLREVKVLKE MASQQGEAMS GPLHIGLIPT VGPYLLPQII PMLHRAFPKL
     EMYLHEAQTH QLLAQLDSGK LDCAILAMVK ESEAFIEVPL FDEPMKLAIY QDHPWANRER
     VAMSDLSGEK LLMLEDGHCL RDQAMGFCFQ AGADEDTHFR ATSLETLRNM VAAGSGITLL
     PSLAVPQERI RDGVCYLPCY KPEPKRTIAL VYRPGSPLRG RYEQLADSVR EHMQLHMEKL
     SAQSA