ID   OXYR_MYCXE              Reviewed;         189 AA.
AC   O87883;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   25-MAY-2022, entry version 72.
DE   RecName: Full=Probable hydrogen peroxide-inducible genes activator;
DE   Flags: Fragment;
GN   Name=oxyR;
OS   Mycobacterium xenopi.
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium.
OX   NCBI_TaxID=1789;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 19250 / DSM 43995 / CIP 104035 / JCM 15661 / NCTC 10042 / TMC
RC   1482;
RX   PubMed=9733688; DOI=10.1128/jb.180.18.4856-4864.1998;
RA   Pagan-Ramos E., Song J., McFalone M., Mudd M.H., Deretic V.;
RT   "Oxidative stress response and characterization of the oxyR-ahpC and furA-
RT   katG loci in Mycobacterium marinum.";
RL   J. Bacteriol. 180:4856-4864(1998).
CC   -!- FUNCTION: Required for the induction the katG gene for catalase.
CC       Involved in the response to hydrogen peroxide (By similarity).
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000305}.
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DR   EMBL; U43810; AAC61664.1; -; Genomic_DNA.
DR   AlphaFoldDB; O87883; -.
DR   SMR; O87883; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   PRINTS; PR00039; HTHLYSR.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
KW   Activator; DNA-binding; Transcription; Transcription regulation.
FT   CHAIN           1..>189
FT                   /note="Probable hydrogen peroxide-inducible genes
FT                   activator"
FT                   /id="PRO_0000105737"
FT   DOMAIN          8..65
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
FT   DNA_BIND        25..44
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
FT   NON_TER         189
SQ   SEQUENCE   189 AA;  19705 MW;  E505FAA97DC45C8B CRC64;
     MADKSYQPTL AGLRAFAAVA EKQHFGSAAS ALGVNQSTLS QALAGLESGL GVRLIERSTR
     RVFLTPEGRQ LLPHARAVLE AVDAFTAAAA GASDPLQGSL RLGLIPTMAP YVLPTVLAGL
     AERLPALTLR VVEDQTERLL AALREGALDA ALIALPAETS GLSAVPIYDE DFVLALPPGH
     PLSGKRRVP