ID   OXYR_PECCC              Reviewed;         302 AA.
AC   P71318;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   25-MAY-2022, entry version 88.
DE   RecName: Full=Hydrogen peroxide-inducible genes activator;
GN   Name=oxyR;
OS   Pectobacterium carotovorum subsp. carotovorum (Erwinia carotovora subsp.
OS   carotovora).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Pectobacteriaceae; Pectobacterium.
OX   NCBI_TaxID=555;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=71;
RX   PubMed=9809430; DOI=10.1111/j.1574-6968.1998.tb13242.x;
RA   Calcutt M.J., Lewis M.S., Eisenstark A.;
RT   "The oxyR gene from Erwinia carotovora: cloning, sequence analysis and
RT   expression in Escherichia coli.";
RL   FEMS Microbiol. Lett. 167:295-301(1998).
CC   -!- FUNCTION: Required for the induction of a regulon of hydrogen peroxide
CC       inducible genes such as catalase and glutathione-reductase.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000305}.
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DR   EMBL; U74302; AAC72241.1; -; Genomic_DNA.
DR   RefSeq; WP_010308165.1; NZ_VBUA01000012.1.
DR   AlphaFoldDB; P71318; -.
DR   SMR; P71318; -.
DR   PRIDE; P71318; -.
DR   GeneID; 51387624; -.
DR   GeneID; 61410017; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   PRINTS; PR00039; HTHLYSR.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
KW   Activator; DNA-binding; Transcription; Transcription regulation.
FT   CHAIN           1..302
FT                   /note="Hydrogen peroxide-inducible genes activator"
FT                   /id="PRO_0000105731"
FT   DOMAIN          1..58
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
FT   DNA_BIND        18..37
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
SQ   SEQUENCE   302 AA;  34178 MW;  95EF2A70C6B5A991 CRC64;
     MNIRDLEYLV ALAEHRHFRR AADSCHVSQP TLSGQIRKLE DELGVMLLER TSRKVLFTQA
     GLLLVEQART VLREVKVLKE MASQQGETMS GPLHIGLIPT VGPYLLPQII PMLHRTFPKL
     EMYLHEAQTH QLLAQLDSGK LDCAILAMVK ESEAFIEVPL FDEPMKLAIY QDHPWANRER
     VAMSDLAGEK LLMLEDGHCL RDQAMGFCFQ AGADEDTHFR ATSLETLRNM VAAGSGITLL
     PALSVPRERE RDGVCYLPCY KPEPKRTIAL VYRPGSPLRG RYEQLADTIR EHMQGYMETL
     SK