ID   P100_HHV7J              Reviewed;         755 AA.
AC   P52519;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   23-FEB-2022, entry version 61.
DE   RecName: Full=Large structural phosphoprotein;
DE   AltName: Full=100 kDa phosphoprotein;
DE            Short=pp100;
GN   Name=U11;
OS   Human herpesvirus 7 (strain JI) (HHV-7) (Human T lymphotropic virus).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Betaherpesvirinae; Roseolovirus.
OX   NCBI_TaxID=57278;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=8709220; DOI=10.1128/jvi.70.9.5975-5989.1996;
RA   Nicholas J.;
RT   "Determination and analysis of the complete nucleotide sequence of human
RT   herpesvirus.";
RL   J. Virol. 70:5975-5989(1996).
CC   -!- SUBCELLULAR LOCATION: Virion tegument {ECO:0000305}. Note=Also found in
CC       dense bodies. {ECO:0000250}.
CC   -!- PTM: Phosphorylated at multiple sites. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the herpesviridae large structural
CC       phosphoprotein family. {ECO:0000305}.
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DR   EMBL; U43400; AAC54672.1; -; Genomic_DNA.
DR   PIR; T41912; T41912.
DR   SMR; P52519; -.
DR   PRIDE; P52519; -.
DR   Proteomes; UP000009246; Genome.
DR   GO; GO:0019033; C:viral tegument; IEA:UniProtKB-SubCell.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   InterPro; IPR010340; Herpes_UL11/UL32.
DR   Pfam; PF06070; Herpes_UL32; 1.
PE   3: Inferred from homology;
KW   Phosphoprotein; Reference proteome; Virion; Virion tegument.
FT   CHAIN           1..755
FT                   /note="Large structural phosphoprotein"
FT                   /id="PRO_0000116301"
FT   REGION          312..333
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          522..555
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        534..555
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   755 AA;  86580 MW;  4083744CCC3F91DA CRC64;
     MKMSHLPFAW ISDEAKCFLS RFFENISSLP VVDIRENPWI LSQCIVKTGN SINNVKTLYN
     NLILWIYFHQ TLCKKKPDYE EVWQEILKVQ KILKDYLEQR QMITDYSSLT SFNKVGFETE
     FKNVAKDLLK LGSFLRWGTV THAADYVNLT TEERAEIGEN LQKAKNNMLS FTIYQIVDPW
     NENGYYVTNI NRLLYLGNLL ITLHGSWMNM EKLALNTINE KKNAILKAIE NNKNFVSIYS
     YQILSLPLTS HRVTSFFKIL TEDFDVITKS LELHALPVKS TWDDRVKFTP EPIQTFKVLT
     DLSKSSLSNQ FESSSKKTSH GSSFNPEPFI KTEQRSNNTL SKDLFVGSED GLLSSVKKDS
     MILDEPRNST SINNSKKMHR ILQTEILDLT DQTMHRPEDK VNQFNEIAVA PDGINQVIDT
     LSKLDLHNSN KVIDIVSSPK VNVVQLPKNK IDYHSTFFLP ENEVNRQNGV QSRDQLSKNS
     TNDLQKILEL RERIKTIKQN NEDIFKLPSE KRRKEIVHEN LQSFDDEHNE MSLPPQDQKS
     IKQKNGNKAN SSTKTLNMIG TNDVNASMKE KESASSAKKN QLVKDVKWTP SSSLLDLSRR
     NDLLQKELFE SGLGEKVKKL LTDFTDTISL EERSLKDVLE PPKKTDVSNI ATFNDNNLKN
     LLNSRKRDPL FQNFSFTEKM QPVRSPFFLP NAEIQDFDSG SLLTGKETQN TIFGASKAQE
     NGDKDLIDLE NSVQKDDDIV NKLVSHLTHS EEDVV