P10_ASFB7
ID P10_ASFB7 Reviewed; 78 AA.
AC Q89769;
DT 05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 23-FEB-2022, entry version 60.
DE RecName: Full=Structural DNA-binding protein p10;
DE Short=p10;
GN OrderedLocusNames=Ba71V-049; ORFNames=K78R;
OS African swine fever virus (strain Badajoz 1971 Vero-adapted) (Ba71V)
OS (ASFV).
OC Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC Asfuvirales; Asfarviridae; Asfivirus.
OX NCBI_TaxID=10498;
OH NCBI_TaxID=6937; Ornithodoros (relapsing fever ticks).
OH NCBI_TaxID=9823; Sus scrofa (Pig).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 2-16, AND FUNCTION.
RX PubMed=8503790; DOI=10.1007/bf01318999;
RA Munoz M., Freije J.M.P., Salas M.L., Vinuela E., Lopez-Otin C.;
RT "Structure and expression in E. coli of the gene coding for protein p10 of
RT African swine fever virus.";
RL Arch. Virol. 130:93-107(1993).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=11831707; DOI=10.1006/viro.1995.1149;
RA Yanez R.J., Rodriguez J.M., Nogal M.L., Yuste L., Enriquez C.,
RA Rodriguez J.F., Vinuela E.;
RT "Analysis of the complete nucleotide sequence of African swine fever
RT virus.";
RL Virology 208:249-278(1995).
RN [3]
RP SUBCELLULAR LOCATION.
RX PubMed=30185597; DOI=10.1128/jvi.01293-18;
RA Alejo A., Matamoros T., Guerra M., Andres G.;
RT "A Proteomic Atlas of the African Swine Fever Virus Particle.";
RL J. Virol. 92:0-0(2018).
RN [4]
RP INDUCTION.
RX PubMed=32075923; DOI=10.1128/jvi.00119-20;
RA Cackett G., Matelska D., Sykora M., Portugal R., Malecki M., Baehler J.,
RA Dixon L., Werner F.;
RT "The African Swine Fever Virus Transcriptome.";
RL J. Virol. 94:0-0(2020).
CC -!- FUNCTION: May play a role in genome packaging through direct
CC interaction with viral DNA. Binds to ssDNA and dsDNA with the same
CC apparent affinity in vitro. {ECO:0000269|PubMed:8503790}.
CC -!- SUBCELLULAR LOCATION: Virion {ECO:0000269|PubMed:30185597}. Note=Found
CC in association with the viral nucleoid. {ECO:0000269|PubMed:30185597}.
CC -!- INDUCTION: Expressed in the early phase of the viral replicative cycle.
CC {ECO:0000269|PubMed:32075923}.
CC -!- SIMILARITY: Belongs to the asfivirus P10 family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; X68563; CAA48564.1; -; Genomic_DNA.
DR EMBL; U18466; AAA65279.1; -; Genomic_DNA.
DR PIR; S29971; S29971.
DR RefSeq; NP_042743.1; NC_001659.2.
DR SMR; Q89769; -.
DR GeneID; 22220431; -.
DR KEGG; vg:22220431; -.
DR Proteomes; UP000000624; Genome.
DR GO; GO:0039642; C:virion nucleoid; IDA:CACAO.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
PE 1: Evidence at protein level;
KW Direct protein sequencing; DNA-binding; Early protein; Reference proteome;
KW Virion.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000269|PubMed:8503790"
FT CHAIN 2..78
FT /note="Structural DNA-binding protein p10"
FT /id="PRO_0000373387"
FT REGION 1..41
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..39
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 78 AA; 8426 MW; D8F98FBADF1D8979 CRC64;
MPTKAGTKST ANKKTTKGSS KSGSSRGHTG KTHASSSMHS GMLYKDMVNI ARSRGIPIYQ
NGSRLTKSEL EKKIKRSK