ID   P10_NPVAC               Reviewed;          94 AA.
AC   P04870;
DT   13-AUG-1987, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 2.
DT   23-FEB-2022, entry version 66.
DE   RecName: Full=Protein p10;
DE   AltName: Full=Fibrous body protein;
GN   Name=P10;
OS   Autographa californica nuclear polyhedrosis virus (AcMNPV).
OC   Viruses; Naldaviricetes; Lefavirales; Baculoviridae; Alphabaculovirus.
OX   NCBI_TaxID=46015;
OH   NCBI_TaxID=7088; Lepidoptera (butterflies and moths).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Kuzio J., Rohel D.Z., Curry C.J., Krebs A., Carstens E.B., Faulkner P.;
RT   "Nucleotide sequence of the p10 polypeptide gene of Autographa californica
RT   nuclear polyhedrosis virus.";
RL   Virology 139:414-418(1984).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C6;
RX   PubMed=8030224; DOI=10.1006/viro.1994.1380;
RA   Ayres M.D., Howard S.C., Kuzio J., Lopez-Ferber M., Possee R.D.;
RT   "The complete DNA sequence of Autographa californica nuclear polyhedrosis
RT   virus.";
RL   Virology 202:586-605(1994).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-79.
RX   PubMed=3023539; DOI=10.1099/0022-1317-67-11-2565;
RA   Liu A., Qin J., Rankin C., Hardin S.E., Weaver R.F.;
RT   "Nucleotide sequence of a portion of the Autographa californica nuclear
RT   polyhedrosis virus genome containing the EcoRI site-rich region (hr5) and
RT   an open reading frame just 5' of the p10 gene.";
RL   J. Gen. Virol. 67:2565-2570(1986).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-20.
RX   PubMed=6090702; DOI=10.1128/jvi.52.1.255-265.1984;
RA   Luebbert H., Doerfler W.;
RT   "Transcription of overlapping sets of RNAs from the genome of Autographa
RT   californica nuclear polyhedrosis virus: a novel method for mapping RNAs.";
RL   J. Virol. 52:255-265(1984).
RN   [5]
RP   SUBCELLULAR LOCATION, AND FUNCTION.
RX   PubMed=3128641; DOI=10.1099/0022-1317-69-4-765;
RA   Vlak J.M., Klinkenberg F.A., Zaal K.J., Usmany M., Klinge-Roode E.C.,
RA   Geervliet J.B., Roosien J., van Lent J.W.;
RT   "Functional studies on the p10 gene of Autographa californica nuclear
RT   polyhedrosis virus using a recombinant expressing a p10-beta-galactosidase
RT   fusion gene.";
RL   J. Gen. Virol. 69:765-776(1988).
RN   [6]
RP   SUBCELLULAR LOCATION, AND FUNCTION.
RX   PubMed=14698669; DOI=10.1016/j.virol.2003.08.035;
RA   Patmanidi A.L., Possee R.D., King L.A.;
RT   "Formation of P10 tubular structures during AcMNPV infection depends on the
RT   integrity of host-cell microtubules.";
RL   Virology 317:308-320(2003).
RN   [7]
RP   FUNCTION.
RX   PubMed=17481692; DOI=10.1016/j.virol.2007.03.051;
RA   Dong C., Deng F., Li D., Wang H., Hu Z.;
RT   "The heptad repeats region is essential for AcMNPV P10 filament formation
RT   and not the proline-rich or the C-terminus basic regions.";
RL   Virology 365:390-397(2007).
RN   [8]
RP   FUNCTION.
RX   PubMed=19264658; DOI=10.1099/vir.0.010397-0;
RA   Wang L., Salem T.Z., Campbell D.J., Turney C.M., Kumar C.M., Cheng X.W.;
RT   "Characterization of a virion occlusion-defective Autographa californica
RT   multiple nucleopolyhedrovirus mutant lacking the p26, p10 and p74 genes.";
RL   J. Gen. Virol. 90:1641-1648(2009).
CC   -!- FUNCTION: Plays a role in the proper virion occlusion of the polyhedra.
CC       Forms extensive fibrillar structures in both host nucleus and
CC       cytoplasm. Involved in the liberation of polyhedra from infected insect
CC       cells. {ECO:0000269|PubMed:14698669, ECO:0000269|PubMed:17481692,
CC       ECO:0000269|PubMed:19264658, ECO:0000269|PubMed:3128641}.
CC   -!- SUBCELLULAR LOCATION: Host cytoplasm {ECO:0000269|PubMed:14698669,
CC       ECO:0000269|PubMed:3128641}. Host nucleus {ECO:0000269|PubMed:14698669,
CC       ECO:0000269|PubMed:3128641}.
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DR   EMBL; M10023; AAA46726.1; -; Genomic_DNA.
DR   EMBL; L22858; AAA66767.1; -; Genomic_DNA.
DR   EMBL; K02701; AAA46723.1; -; Genomic_DNA.
DR   EMBL; X04611; CAA28281.1; -; Genomic_DNA.
DR   PIR; B72867; B72867.
DR   RefSeq; NP_054167.1; NC_001623.1.
DR   SMR; P04870; -.
DR   iPTMnet; P04870; -.
DR   GeneID; 1403970; -.
DR   KEGG; vg:1403970; -.
DR   Proteomes; UP000008292; Genome.
DR   GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0039679; C:viral occlusion body; IEA:UniProtKB-KW.
DR   InterPro; IPR008702; NPV_P10.
DR   Pfam; PF05531; NPV_P10; 1.
PE   4: Predicted;
KW   Host cytoplasm; Host nucleus; Late protein; Reference proteome;
KW   Viral occlusion body.
FT   CHAIN           1..94
FT                   /note="Protein p10"
FT                   /id="PRO_0000132879"
FT   CONFLICT        77
FT                   /note="T -> S (in Ref. 1 and 3)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   94 AA;  10310 MW;  EFB576D6930F3F0C CRC64;
     MSKPNVLTQI LDAVTETNTK VDSVQTQLNG LEESFQLLDG LPAQLTDLNT KISEIQSILT
     GDIVPDLPDS LKPKLKTQAF ELDSDARRGK RSSK