P12L1_HUMAN
ID P12L1_HUMAN Reviewed; 428 AA.
AC Q3SYA9;
DT 26-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT 15-MAY-2007, sequence version 2.
DT 25-MAY-2022, entry version 83.
DE RecName: Full=Putative POM121-like protein 1;
GN Name=POM121L1P; Synonyms=POM121L1;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=10591208; DOI=10.1038/990031;
RA Dunham I., Hunt A.R., Collins J.E., Bruskiewich R., Beare D.M., Clamp M.,
RA Smink L.J., Ainscough R., Almeida J.P., Babbage A.K., Bagguley C.,
RA Bailey J., Barlow K.F., Bates K.N., Beasley O.P., Bird C.P., Blakey S.E.,
RA Bridgeman A.M., Buck D., Burgess J., Burrill W.D., Burton J., Carder C.,
RA Carter N.P., Chen Y., Clark G., Clegg S.M., Cobley V.E., Cole C.G.,
RA Collier R.E., Connor R., Conroy D., Corby N.R., Coville G.J., Cox A.V.,
RA Davis J., Dawson E., Dhami P.D., Dockree C., Dodsworth S.J., Durbin R.M.,
RA Ellington A.G., Evans K.L., Fey J.M., Fleming K., French L., Garner A.A.,
RA Gilbert J.G.R., Goward M.E., Grafham D.V., Griffiths M.N.D., Hall C.,
RA Hall R.E., Hall-Tamlyn G., Heathcott R.W., Ho S., Holmes S., Hunt S.E.,
RA Jones M.C., Kershaw J., Kimberley A.M., King A., Laird G.K., Langford C.F.,
RA Leversha M.A., Lloyd C., Lloyd D.M., Martyn I.D., Mashreghi-Mohammadi M.,
RA Matthews L.H., Mccann O.T., Mcclay J., Mclaren S., McMurray A.A.,
RA Milne S.A., Mortimore B.J., Odell C.N., Pavitt R., Pearce A.V., Pearson D.,
RA Phillimore B.J.C.T., Phillips S.H., Plumb R.W., Ramsay H., Ramsey Y.,
RA Rogers L., Ross M.T., Scott C.E., Sehra H.K., Skuce C.D., Smalley S.,
RA Smith M.L., Soderlund C., Spragon L., Steward C.A., Sulston J.E.,
RA Swann R.M., Vaudin M., Wall M., Wallis J.M., Whiteley M.N., Willey D.L.,
RA Williams L., Williams S.A., Williamson H., Wilmer T.E., Wilming L.,
RA Wright C.L., Hubbard T., Bentley D.R., Beck S., Rogers J., Shimizu N.,
RA Minoshima S., Kawasaki K., Sasaki T., Asakawa S., Kudoh J., Shintani A.,
RA Shibuya K., Yoshizaki Y., Aoki N., Mitsuyama S., Roe B.A., Chen F., Chu L.,
RA Crabtree J., Deschamps S., Do A., Do T., Dorman A., Fang F., Fu Y., Hu P.,
RA Hua A., Kenton S., Lai H., Lao H.I., Lewis J., Lewis S., Lin S.-P., Loh P.,
RA Malaj E., Nguyen T., Pan H., Phan S., Qi S., Qian Y., Ray L., Ren Q.,
RA Shaull S., Sloan D., Song L., Wang Q., Wang Y., Wang Z., White J.,
RA Willingham D., Wu H., Yao Z., Zhan M., Zhang G., Chissoe S., Murray J.,
RA Miller N., Minx P., Fulton R., Johnson D., Bemis G., Bentley D.,
RA Bradshaw H., Bourne S., Cordes M., Du Z., Fulton L., Goela D., Graves T.,
RA Hawkins J., Hinds K., Kemp K., Latreille P., Layman D., Ozersky P.,
RA Rohlfing T., Scheet P., Walker C., Wamsley A., Wohldmann P., Pepin K.,
RA Nelson J., Korf I., Bedell J.A., Hillier L.W., Mardis E., Waterston R.,
RA Wilson R., Emanuel B.S., Shaikh T., Kurahashi H., Saitta S., Budarf M.L.,
RA McDermid H.E., Johnson A., Wong A.C.C., Morrow B.E., Edelmann L., Kim U.J.,
RA Shizuya H., Simon M.I., Dumanski J.P., Peyrard M., Kedra D., Seroussi E.,
RA Fransson I., Tapia I., Bruder C.E., O'Brien K.P., Wilkinson P.,
RA Bodenteich A., Hartman K., Hu X., Khan A.S., Lane L., Tilahun Y.,
RA Wright H.;
RT "The DNA sequence of human chromosome 22.";
RL Nature 402:489-495(1999).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- INTERACTION:
CC Q3SYA9; Q13077: TRAF1; NbExp=3; IntAct=EBI-10241319, EBI-359224;
CC Q3SYA9; Q15654: TRIP6; NbExp=3; IntAct=EBI-10241319, EBI-742327;
CC -!- SIMILARITY: Belongs to the POM121 family. {ECO:0000305}.
CC -!- CAUTION: Could be the product of a pseudogene. {ECO:0000305}.
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DR EMBL; AC007050; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC103891; -; NOT_ANNOTATED_CDS; mRNA.
DR AlphaFoldDB; Q3SYA9; -.
DR SMR; Q3SYA9; -.
DR IntAct; Q3SYA9; 2.
DR STRING; 9606.ENSP00000481613; -.
DR iPTMnet; Q3SYA9; -.
DR PhosphoSitePlus; Q3SYA9; -.
DR BioMuta; HGNC:16439; -.
DR DMDM; 150385310; -.
DR MassIVE; Q3SYA9; -.
DR PaxDb; Q3SYA9; -.
DR PeptideAtlas; Q3SYA9; -.
DR PRIDE; Q3SYA9; -.
DR GeneCards; POM121L1P; -.
DR HGNC; HGNC:16439; POM121L1P.
DR neXtProt; NX_Q3SYA9; -.
DR eggNOG; ENOG502RU3H; Eukaryota.
DR InParanoid; Q3SYA9; -.
DR PhylomeDB; Q3SYA9; -.
DR PathwayCommons; Q3SYA9; -.
DR SignaLink; Q3SYA9; -.
DR Pharos; Q3SYA9; Tdark.
DR PRO; PR:Q3SYA9; -.
DR Proteomes; UP000005640; Unplaced.
DR RNAct; Q3SYA9; protein.
DR InterPro; IPR043220; POM121-like_prot_1.
DR PANTHER; PTHR15566; PTHR15566; 1.
PE 5: Uncertain;
KW Reference proteome.
FT CHAIN 1..428
FT /note="Putative POM121-like protein 1"
FT /id="PRO_0000292038"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 36..204
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 254..293
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 306..384
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 402..428
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 40..57
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 98..131
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 144..169
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 258..272
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 329..347
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 428 AA; 45448 MW; FE99774ADDAB9AD9 CRC64;
MDSLWGPGAG SHPFGVHNSR LSPDLCPGKI VLRALKESGA GMPEQDKDPR VQENPGDQRR
VPEVTGDAPS AFRPLRDNGG LSPFVPGPGP LQTDLHAQRS EIRYNQTSQT SWTSSCTNRN
AISSSYSSTG GLPGLKRRRG PASSHCQLTL SSSKTVSEDR PQAVSSGHTQ CEKVAEIAPG
QTLALRNDSS RSEASRPSTR KFPLLPRRRG EPLMLPPPVE LGYRVTAEDL DWEKEAAFQC
IKSALQVEDK AISDCRPSRP SHTLSSLATG ASGLPAVSKA PSMDAQQERH KSQDCLGLVA
PLASATEVPS TAPMSGEKHR PPGPLFSSSD PLPATSSHSQ DSAQVTSLIP APFPAASMDA
GMRRTRPGTS APAAAAAAPP PSTLNRTLGS LLEWMEALHI SGPQPQLQQV PRGQNQRSQT
SRTSSCPK
