ID   P12_ASFB7               Reviewed;          61 AA.
AC   P32510;
DT   01-OCT-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1993, sequence version 1.
DT   03-AUG-2022, entry version 66.
DE   RecName: Full=Inner membrane protein p12;
DE   AltName: Full=Protein p12;
GN   OrderedLocusNames=Ba71V-98; ORFNames=O61R;
OS   African swine fever virus (strain Badajoz 1971 Vero-adapted) (Ba71V)
OS   (ASFV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Asfuvirales; Asfarviridae; Asfivirus.
OX   NCBI_TaxID=10498;
OH   NCBI_TaxID=6937; Ornithodoros (relapsing fever ticks).
OH   NCBI_TaxID=9823; Sus scrofa (Pig).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], INDUCTION, AND SUBUNIT.
RX   PubMed=1583732; DOI=10.1128/jvi.66.6.3860-3868.1992;
RA   Alcami A., Angulo A., Lopez-Otin C., Munoz M., Freije J.M.P.,
RA   Carrascosa A.L., Vinuela E.;
RT   "Amino acid sequence and structural properties of protein p12, an African
RT   swine fever virus attachment protein.";
RL   J. Virol. 66:3860-3868(1992).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=11831707; DOI=10.1006/viro.1995.1149;
RA   Yanez R.J., Rodriguez J.M., Nogal M.L., Yuste L., Enriquez C.,
RA   Rodriguez J.F., Vinuela E.;
RT   "Analysis of the complete nucleotide sequence of African swine fever
RT   virus.";
RL   Virology 208:249-278(1995).
RN   [3]
RP   SUBCELLULAR LOCATION.
RX   PubMed=30185597; DOI=10.1128/jvi.01293-18;
RA   Alejo A., Matamoros T., Guerra M., Andres G.;
RT   "A Proteomic Atlas of the African Swine Fever Virus Particle.";
RL   J. Virol. 92:0-0(2018).
RN   [4]
RP   INDUCTION.
RX   PubMed=32075923; DOI=10.1128/jvi.00119-20;
RA   Cackett G., Matelska D., Sykora M., Portugal R., Malecki M., Baehler J.,
RA   Dixon L., Werner F.;
RT   "The African Swine Fever Virus Transcriptome.";
RL   J. Virol. 94:0-0(2020).
CC   -!- SUBUNIT: Homomultimer; disulfide-linked. {ECO:0000269|PubMed:1583732}.
CC   -!- SUBCELLULAR LOCATION: Virion membrane {ECO:0000305|PubMed:30185597};
CC       Single-pass membrane protein {ECO:0000305}. Note=Part of the virion
CC       inner membrane. {ECO:0000269|PubMed:30185597}.
CC   -!- INDUCTION: Expressed in the late phase of the viral replicative cycle.
CC       {ECO:0000269|PubMed:1583732, ECO:0000269|PubMed:32075923}.
CC   -!- PTM: Not glycosylated. {ECO:0000269|PubMed:1583732}.
CC   -!- SIMILARITY: Belongs to the asfivirus inner membrane protein p12 family.
CC       {ECO:0000305}.
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DR   EMBL; M84178; AAA42725.1; -; Genomic_DNA.
DR   EMBL; M84186; AAA42723.1; -; Genomic_DNA.
DR   EMBL; U18466; AAA65327.1; -; Genomic_DNA.
DR   PIR; A41998; WMXF12.
DR   RefSeq; NP_042791.1; NC_001659.2.
DR   SMR; P32510; -.
DR   GeneID; 22220327; -.
DR   KEGG; vg:22220327; -.
DR   Proteomes; UP000000624; Genome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0055036; C:virion membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0019062; P:virion attachment to host cell; IDA:CACAO.
PE   1: Evidence at protein level;
KW   Disulfide bond; Late protein; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix; Virion.
FT   CHAIN           1..61
FT                   /note="Inner membrane protein p12"
FT                   /id="PRO_0000221943"
FT   TRANSMEM        16..36
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   61 AA;  6679 MW;  0B95F1A32FD22732 CRC64;
     MALDGSSGGG SNVETLLIVA IIVVIMAIML YYFWWMPRQQ KKCSKAEECT CNNGSCSLKT
     S