ID   P152_METTH              Reviewed;         186 AA.
AC   O26255;
DT   21-FEB-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   03-AUG-2022, entry version 125.
DE   RecName: Full=Protein MTH_152;
GN   OrderedLocusNames=MTH_152;
OS   Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM
OS   10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum).
OC   Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC   Methanobacteriales; Methanobacteriaceae; Methanothermobacter.
OX   NCBI_TaxID=187420;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H;
RX   PubMed=9371463; DOI=10.1128/jb.179.22.7135-7155.1997;
RA   Smith D.R., Doucette-Stamm L.A., Deloughery C., Lee H.-M., Dubois J.,
RA   Aldredge T., Bashirzadeh R., Blakely D., Cook R., Gilbert K., Harrison D.,
RA   Hoang L., Keagle P., Lumm W., Pothier B., Qiu D., Spadafora R., Vicare R.,
RA   Wang Y., Wierzbowski J., Gibson R., Jiwani N., Caruso A., Bush D.,
RA   Safer H., Patwell D., Prabhakar S., McDougall S., Shimer G., Goyal A.,
RA   Pietrovski S., Church G.M., Daniels C.J., Mao J.-I., Rice P., Noelling J.,
RA   Reeve J.N.;
RT   "Complete genome sequence of Methanobacterium thermoautotrophicum deltaH:
RT   functional analysis and comparative genomics.";
RL   J. Bacteriol. 179:7135-7155(1997).
RN   [2]
RP   X-RAY CRYSTALLOGRAPHY (2.2 ANGSTROMS).
RX   PubMed=11017201; DOI=10.1038/82823;
RA   Christendat D., Yee A., Dharamsi A., Kluger Y., Savchenko A., Cort J.R.,
RA   Booth V., Mackereth C.D., Saridakis V., Ekiel I., Kozlov G., Maxwell K.L.,
RA   Wu N., McIntosh L.P., Gehring K., Kennedy M.A., Davidson A.R., Pai E.F.,
RA   Gerstein M., Edwards A.M., Arrowsmith C.H.;
RT   "Structural proteomics of an archaeon.";
RL   Nat. Struct. Biol. 7:903-909(2000).
CC   -!- COFACTOR:
CC       Name=FMN; Xref=ChEBI:CHEBI:58210;
CC   -!- SUBUNIT: Homodimer.
CC   -!- SIMILARITY: Belongs to the flavoredoxin family. {ECO:0000305}.
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DR   EMBL; AE000666; AAB84658.1; -; Genomic_DNA.
DR   PIR; G69069; G69069.
DR   PDB; 1EJE; X-ray; 2.20 A; A=1-186.
DR   PDBsum; 1EJE; -.
DR   AlphaFoldDB; O26255; -.
DR   SMR; O26255; -.
DR   PRIDE; O26255; -.
DR   EnsemblBacteria; AAB84658; AAB84658; MTH_152.
DR   KEGG; mth:MTH_152; -.
DR   PATRIC; fig|187420.15.peg.124; -.
DR   HOGENOM; CLU_059021_3_1_2; -.
DR   OMA; APFSCFT; -.
DR   EvolutionaryTrace; O26255; -.
DR   Proteomes; UP000005223; Chromosome.
DR   GO; GO:0010181; F:FMN binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProt.
DR   Gene3D; 2.30.110.10; -; 1.
DR   InterPro; IPR002563; Flavin_Rdtase-like_dom.
DR   InterPro; IPR012349; Split_barrel_FMN-bd.
DR   Pfam; PF01613; Flavin_Reduct; 1.
DR   SMART; SM00903; Flavin_Reduct; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Flavoprotein; FMN; Reference proteome.
FT   CHAIN           1..186
FT                   /note="Protein MTH_152"
FT                   /id="PRO_0000085528"
FT   TURN            3..5
FT                   /evidence="ECO:0007829|PDB:1EJE"
FT   HELIX           11..16
FT                   /evidence="ECO:0007829|PDB:1EJE"
FT   STRAND          24..29
FT                   /evidence="ECO:0007829|PDB:1EJE"
FT   STRAND          35..40
FT                   /evidence="ECO:0007829|PDB:1EJE"
FT   STRAND          42..47
FT                   /evidence="ECO:0007829|PDB:1EJE"
FT   TURN            48..51
FT                   /evidence="ECO:0007829|PDB:1EJE"
FT   STRAND          52..57
FT                   /evidence="ECO:0007829|PDB:1EJE"
FT   HELIX           62..70
FT                   /evidence="ECO:0007829|PDB:1EJE"
FT   STRAND          72..77
FT                   /evidence="ECO:0007829|PDB:1EJE"
FT   HELIX           80..82
FT                   /evidence="ECO:0007829|PDB:1EJE"
FT   HELIX           83..88
FT                   /evidence="ECO:0007829|PDB:1EJE"
FT   HELIX           99..103
FT                   /evidence="ECO:0007829|PDB:1EJE"
FT   STRAND          111..115
FT                   /evidence="ECO:0007829|PDB:1EJE"
FT   STRAND          122..135
FT                   /evidence="ECO:0007829|PDB:1EJE"
FT   STRAND          138..150
FT                   /evidence="ECO:0007829|PDB:1EJE"
FT   HELIX           162..165
FT                   /evidence="ECO:0007829|PDB:1EJE"
FT   STRAND          167..172
FT                   /evidence="ECO:0007829|PDB:1EJE"
FT   STRAND          175..178
FT                   /evidence="ECO:0007829|PDB:1EJE"
SQ   SEQUENCE   186 AA;  20323 MW;  6997E8C6D9234A89 CRC64;
     MMSMDFEDFP VESAHRILTP RPTVMVTTVD EEGNINAAPF SFTMPVSIDP PVVAFASAPD
     HHTARNIEST HEFVINITPA DIIERMWVTA RDIPAGENEL EAAGLAWTSS RRVKPPRIVE
     APGHLECELL RMFEVGDHNL ITGSVVSASV RSGAVKEGLL DVESVKPVLH VGGNKFVVGD
     HVRHVE