ID   P165A_ARATH             Reviewed;          18 AA.
AC   P0DKI9;
DT   24-JUN-2015, integrated into UniProtKB/Swiss-Prot.
DT   24-JUN-2015, sequence version 1.
DT   25-MAY-2022, entry version 18.
DE   RecName: Full=Peptide encoded by miPEP165a {ECO:0000303|PubMed:25807486};
GN   Name=miPEP165a {ECO:0000303|PubMed:25807486};
GN   OrderedLocusNames=At1g01184 {ECO:0000305};
GN   ORFNames=F6F3 {ECO:0000312|EMBL:AC023628};
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, AND TISSUE SPECIFICITY.
RC   STRAIN=cv. Columbia;
RX   PubMed=25807486; DOI=10.1038/nature14346;
RA   Lauressergues D., Couzigou J.M., Clemente H.S., Martinez Y., Dunand C.,
RA   Becard G., Combier J.P.;
RT   "Primary transcripts of microRNAs encode regulatory peptides.";
RL   Nature 520:90-93(2015).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130712; DOI=10.1038/35048500;
RA   Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA   Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA   Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA   Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA   Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA   Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA   Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA   Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA   Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA   Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA   Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA   Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA   Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA   Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA   Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT   "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL   Nature 408:816-820(2000).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
CC   -!- FUNCTION: Regulatory peptide encoded by the primary transcript (pri-
CC       miR165a) of the microRNA miR165a that enhances the accumulation of its
CC       corresponding mature miRNA. Acts as a transcriptional activator of its
CC       corresponding pri-miRNA. Addition of synthetic miPEP165a increases the
CC       abundance of miR165a, with consequent increase of root length.
CC       {ECO:0000269|PubMed:25807486}.
CC   -!- TISSUE SPECIFICITY: Expressed in the root endodermis.
CC       {ECO:0000269|PubMed:25807486}.
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DR   EMBL; AC023628; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CP002684; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; P0DKI9; -.
DR   Araport; AT1G01184; -.
DR   PRO; PR:P0DKI9; -.
DR   Proteomes; UP000006548; Chromosome 1.
DR   GO; GO:1902895; P:positive regulation of miRNA transcription; IDA:GO_Central.
DR   GO; GO:2000280; P:regulation of root development; IDA:UniProtKB.
PE   2: Evidence at transcript level;
KW   Activator; Reference proteome; Transcription; Transcription regulation.
FT   PEPTIDE         1..18
FT                   /note="Peptide encoded by miPEP165a"
FT                   /id="PRO_0000433199"
SQ   SEQUENCE   18 AA;  2106 MW;  117FD11DBBE593C3 CRC64;
     MRVKLFQLRG MLSGSRIL