ID   P19_AMCV                Reviewed;         172 AA.
AC   P15960;
DT   01-APR-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1990, sequence version 1.
DT   25-MAY-2022, entry version 64.
DE   RecName: Full=RNA silencing suppressor p19;
DE   AltName: Full=19 kDa symptom severity modulator;
GN   ORFNames=ORF4;
OS   Artichoke mottled crinkle virus (AMCV).
OC   Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Tolucaviricetes;
OC   Tolivirales; Tombusviridae; Procedovirinae; Tombusvirus.
OX   NCBI_TaxID=12142;
OH   NCBI_TaxID=59895; Cynara cardunculus var. scolymus (Globe artichoke) (Cynara scolymus).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RC   STRAIN=Bari-Dr. Gallitelli isolate;
RX   PubMed=2320427; DOI=10.1093/nar/18.5.1300;
RA   Grieco F., Gallitelli D.;
RT   "Nucleotide sequence of the 3'-terminal region of artichoke mottled crinkle
RT   tombusvirus RNA.";
RL   Nucleic Acids Res. 18:1300-1300(1990).
CC   -!- FUNCTION: Viral suppressor of RNA silencing which binds specifically to
CC       silencing RNAs (siRNAs). Acts as a molecular caliper to specifically
CC       select siRNAs based on the length of the duplex region of the RNA (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the tombusvirus protein p19 family.
CC       {ECO:0000305}.
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DR   EMBL; X51456; CAA35823.1; -; Genomic_RNA.
DR   PIR; S08430; NKVGBC.
DR   SMR; P15960; -.
DR   GO; GO:0044423; C:virion component; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.390.180; -; 1.
DR   InterPro; IPR004905; Tombusvirus_p19.
DR   InterPro; IPR036131; VP19_sf.
DR   Pfam; PF03220; Tombus_P19; 1.
DR   SUPFAM; SSF103145; SSF103145; 1.
PE   3: Inferred from homology;
KW   RNA-binding; Suppressor of RNA silencing.
FT   CHAIN           1..172
FT                   /note="RNA silencing suppressor p19"
FT                   /id="PRO_0000222871"
FT   REGION          1..37
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   172 AA;  19280 MW;  5EE2911E6DA96901 CRC64;
     MERVIQGNDA REQANGERWD GGSGGTTSGF KLPDESPSWT EWRIHNDETD SNKDNPLGFK
     ESWGFGKVVF KRYLRYDRTE TSLHRVLGSW TGDSVNYAAS RFLGVNQIGC TYSIRFRGVS
     VTISGGSRTL QHICEMAIRS KQELLQLAPV EVESNVSRGR PEGAEAFKEE SE