ID   P19_PENSV               Reviewed;         172 AA.
AC   Q709N3;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 50.
DE   RecName: Full=RNA silencing suppressor p19;
DE   AltName: Full=19 kDa symptom severity modulator;
GN   ORFNames=ORF4;
OS   Pelargonium necrotic spot virus (PeNSV).
OC   Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Tolucaviricetes;
OC   Tolivirales; Tombusviridae; Procedovirinae; Tombusvirus.
OX   NCBI_TaxID=255587;
OH   NCBI_TaxID=4032; Pelargonium zonale.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=15290378; DOI=10.1007/s00705-004-0319-6;
RA   Heinze C., Wobbe V., Lesemann D.-E., Zhang D.Y., Willingmann P., Adam G.;
RT   "Pelargonium necrotic spot virus: a new member of the genus Tombusvirus.";
RL   Arch. Virol. 149:1527-1539(2004).
CC   -!- FUNCTION: Viral suppressor of RNA silencing which binds specifically to
CC       silencing RNAs (siRNAs). Acts as a molecular caliper to specifically
CC       select siRNAs based on the length of the duplex region of the RNA (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the tombusvirus protein p19 family.
CC       {ECO:0000305}.
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DR   EMBL; AJ607402; CAE55160.1; -; Genomic_RNA.
DR   RefSeq; NP_945118.1; NC_005285.1.
DR   SMR; Q709N3; -.
DR   GeneID; 10216565; -.
DR   KEGG; vg:10216565; -.
DR   Proteomes; UP000202589; Genome.
DR   GO; GO:0044423; C:virion component; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.390.180; -; 1.
DR   InterPro; IPR004905; Tombusvirus_p19.
DR   InterPro; IPR036131; VP19_sf.
DR   Pfam; PF03220; Tombus_P19; 1.
DR   SUPFAM; SSF103145; SSF103145; 1.
PE   3: Inferred from homology;
KW   RNA-binding; Suppressor of RNA silencing.
FT   CHAIN           1..172
FT                   /note="RNA silencing suppressor p19"
FT                   /id="PRO_0000222877"
FT   REGION          153..172
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   172 AA;  19060 MW;  D420F64DDA2D2C55 CRC64;
     MERAVQGGDA REQANSERWD GGCGGTITPF KLSDESPSLH EWRLHHSEEG EDQDHPLGFK
     ESWSFGKVVF KRYLRYGGTE TSLHRALGSW ERNTVNNAAS RFLGFGQIGC TYSIRFRGSC
     LTISGGSRTL QRLIEMAIRT KCTVLQLTPS EVEGNVSGGS PEGIEAFEKE SE