P19_PLV
ID P19_PLV Reviewed; 172 AA.
AC Q8JMT1;
DT 15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2002, sequence version 1.
DT 25-MAY-2022, entry version 52.
DE RecName: Full=RNA silencing suppressor p19;
DE AltName: Full=19 kDa symptom severity modulator;
GN ORFNames=ORF4;
OS Pear latent virus (PeLV).
OC Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Tolucaviricetes;
OC Tolivirales; Tombusviridae; Procedovirinae; Tombusvirus.
OX NCBI_TaxID=197112;
OH NCBI_TaxID=23211; Pyrus communis (Pear) (Pyrus domestica).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RA Russo M., Vovlas C., Rubino L., Grieco F., Martelli G.P.;
RT "Molecular characterization of a tombusvirus isolated from diseased pear
RT trees in southern Italy.";
RL J. Plant Pathol. 84:161-166(2002).
CC -!- FUNCTION: Viral suppressor of RNA silencing which binds specifically to
CC silencing RNAs (siRNAs). Acts as a molecular caliper to specifically
CC select siRNAs based on the length of the duplex region of the RNA (By
CC similarity). {ECO:0000250}.
CC -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the tombusvirus protein p19 family.
CC {ECO:0000305}.
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DR EMBL; AY100482; AAM49806.1; -; Genomic_RNA.
DR SMR; Q8JMT1; -.
DR Proteomes; UP000232449; Genome.
DR GO; GO:0044423; C:virion component; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR Gene3D; 3.30.390.180; -; 1.
DR InterPro; IPR004905; Tombusvirus_p19.
DR InterPro; IPR036131; VP19_sf.
DR Pfam; PF03220; Tombus_P19; 1.
DR SUPFAM; SSF103145; SSF103145; 1.
PE 3: Inferred from homology;
KW RNA-binding; Suppressor of RNA silencing.
FT CHAIN 1..172
FT /note="RNA silencing suppressor p19"
FT /id="PRO_0000222876"
FT REGION 153..172
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 172 AA; 19357 MW; A9596921EB5E6514 CRC64;
MERAIQGSDA REQAYSERWD GGCGGTITPF KLPDESPSLI EWRLHNSEES EDKDNPLGFK
ESWSFGKVVF KRYLRYDGTE ASLHRALGSW ERDTVNNAAS RFLGFGQIGC TYCIRFRGSC
LTISGGSRTL QRLIEMAIRT KRTMLQLTPC EVEGNVSRGS PEGTEAFKEE SE