ID   P20D2_XENTR             Reviewed;         443 AA.
AC   Q501L1;
DT   01-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   07-JUN-2005, sequence version 1.
DT   03-AUG-2022, entry version 89.
DE   RecName: Full=Peptidase M20 domain-containing protein 2;
DE   AltName: Full=Aminoacylase-1-like protein 2;
GN   Name=pm20d2; Synonyms=acy1l2;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase M20A family. {ECO:0000305}.
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DR   EMBL; BC096002; AAH96002.1; -; mRNA.
DR   RefSeq; NP_001027482.1; NM_001032311.1.
DR   AlphaFoldDB; Q501L1; -.
DR   SMR; Q501L1; -.
DR   STRING; 8364.ENSXETP00000011859; -.
DR   PaxDb; Q501L1; -.
DR   DNASU; 613074; -.
DR   GeneID; 613074; -.
DR   KEGG; xtr:613074; -.
DR   CTD; 135293; -.
DR   Xenbase; XB-GENE-969482; pm20d2.
DR   eggNOG; ENOG502QQPD; Eukaryota.
DR   HOGENOM; CLU_031812_1_1_1; -.
DR   InParanoid; Q501L1; -.
DR   OMA; GPWEGIN; -.
DR   OrthoDB; 455218at2759; -.
DR   PhylomeDB; Q501L1; -.
DR   TreeFam; TF332656; -.
DR   Proteomes; UP000008143; Chromosome 5.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000005387; Expressed in liver and 14 other tissues.
DR   GO; GO:0016805; F:dipeptidase activity; IBA:GO_Central.
DR   InterPro; IPR036264; Bact_exopeptidase_dim_dom.
DR   InterPro; IPR002933; Peptidase_M20.
DR   InterPro; IPR011650; Peptidase_M20_dimer.
DR   InterPro; IPR017144; Xaa-Arg_dipeptidase.
DR   Pfam; PF07687; M20_dimer; 1.
DR   Pfam; PF01546; Peptidase_M20; 1.
DR   PIRSF; PIRSF037226; Amidohydrolase_ACY1L2_prd; 1.
DR   SUPFAM; SSF55031; SSF55031; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           1..443
FT                   /note="Peptidase M20 domain-containing protein 2"
FT                   /id="PRO_0000286342"
SQ   SEQUENCE   443 AA;  48018 MW;  01B8AABDC9C736FC CRC64;
     MGPELQGAGG KCSAELSALE ACKQRAAERI QEEAESLCEL SRDIWSRPEL AYQEQQAHET
     LTRFFSSRAG WLLEPHYKLD TAFRAEWSTP LTDNLSQPLH VGFLCEYDAL PSLGHACGHN
     LIAEVGAAAA LGLQGALQCS QPPRPVKITV LGTPAEEDGG GKIDLIEAGA FVDMHVVFMA
     HPAQEDAAYL PDVAEHDVTV KYYGKASHAA AYPWEGVNAL DAAILAYNNL SVLRQQMKPT
     WRAHGIIKNG GVKPNIIPSY SELEFYLRAP SLKELTKLQE KADACFKAAA AATGCRVELS
     SSGHDYYNVL QNKTLAKTYV ENGKKLGMQF AADNLALNSL SGSTDFGNVS FVVPGIHPYF
     YIGSDALNHT EEYTEAAGSK EAQFYALRTA KALAMTALDV LFNPDLLANV CEDFKLIKLI
     EEGNMHVTEK SRESSGGAGC ASR