ID   P22_ASFM2               Reviewed;         170 AA.
AC   P0C9W1;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   05-MAY-2009, sequence version 1.
DT   03-AUG-2022, entry version 32.
DE   RecName: Full=Inner membrane protein p22 {ECO:0000305};
GN   OrderedLocusNames=Mal-002;
OS   African swine fever virus (isolate Tick/Malawi/Lil 20-1/1983) (ASFV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Asfuvirales; Asfarviridae; Asfivirus.
OX   NCBI_TaxID=10500;
OH   NCBI_TaxID=6937; Ornithodoros (relapsing fever ticks).
OH   NCBI_TaxID=85517; Phacochoerus aethiopicus (Warthog).
OH   NCBI_TaxID=41426; Phacochoerus africanus (Warthog).
OH   NCBI_TaxID=273792; Potamochoerus larvatus (Bushpig).
OH   NCBI_TaxID=9823; Sus scrofa (Pig).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Kutish G.F., Rock D.L.;
RT   "African swine fever virus genomes.";
RL   Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Virion membrane {ECO:0000250|UniProtKB:P23169};
CC       Single-pass membrane protein {ECO:0000255}. Host cell membrane
CC       {ECO:0000250|UniProtKB:P23169}; Single-pass membrane protein
CC       {ECO:0000255}. Note=Part of the virion inner membrane.
CC       {ECO:0000250|UniProtKB:P23169}.
CC   -!- INDUCTION: Expressed in the late phase of the viral replicative cycle.
CC       {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the asfivirus inner membrane protein p22 family.
CC       {ECO:0000305}.
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DR   EMBL; AY261361; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Proteomes; UP000000860; Genome.
DR   GO; GO:0020002; C:host cell plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0055036; C:virion membrane; IEA:UniProtKB-SubCell.
PE   3: Inferred from homology;
KW   Early protein; Host cell membrane; Host membrane; Membrane; Transmembrane;
KW   Transmembrane helix; Virion.
FT   CHAIN           1..170
FT                   /note="Inner membrane protein p22"
FT                   /id="PRO_0000373365"
FT   TOPO_DOM        1..3
FT                   /note="Intravirion"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        4..24
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        25..170
FT                   /note="Virion surface"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   170 AA;  19522 MW;  982757B98DBC574D CRC64;
     MSTLLIALIA LIVLLIIILV VFLYYKKQQP PKKVCKVDKD CGSREHCVRG TCSSLSCLDA
     VKMDKRDVKM DSKISSCKFT PNFYHFTDTA AEQEFGKTWH SIKITPSPGE SHTSQEICER
     YCLWGTDDCT GWEYFGDEKN GTCNIYNNPY LALKYTKDHV LYLPRNHKYA