ID   P22_ASFP4               Reviewed;         177 AA.
AC   P0C9W2;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   05-MAY-2009, sequence version 1.
DT   03-AUG-2022, entry version 35.
DE   RecName: Full=Inner membrane protein p22 {ECO:0000305};
GN   OrderedLocusNames=Pret-004;
OS   African swine fever virus (isolate Tick/South Africa/Pretoriuskop Pr4/1996)
OS   (ASFV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Asfuvirales; Asfarviridae; Asfivirus.
OX   NCBI_TaxID=561443;
OH   NCBI_TaxID=6937; Ornithodoros (relapsing fever ticks).
OH   NCBI_TaxID=85517; Phacochoerus aethiopicus (Warthog).
OH   NCBI_TaxID=41426; Phacochoerus africanus (Warthog).
OH   NCBI_TaxID=273792; Potamochoerus larvatus (Bushpig).
OH   NCBI_TaxID=9823; Sus scrofa (Pig).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Kutish G.F., Rock D.L.;
RT   "African swine fever virus genomes.";
RL   Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Virion membrane {ECO:0000250|UniProtKB:P23169};
CC       Single-pass membrane protein {ECO:0000255}. Host cell membrane
CC       {ECO:0000250|UniProtKB:P23169}; Single-pass membrane protein
CC       {ECO:0000255}. Note=Part of the virion inner membrane.
CC       {ECO:0000250|UniProtKB:P23169}.
CC   -!- INDUCTION: Expressed in the late phase of the viral replicative cycle.
CC       {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the asfivirus inner membrane protein p22 family.
CC       {ECO:0000305}.
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DR   EMBL; AY261363; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   SMR; P0C9W2; -.
DR   Proteomes; UP000000859; Genome.
DR   GO; GO:0020002; C:host cell plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0055036; C:virion membrane; IEA:UniProtKB-SubCell.
PE   3: Inferred from homology;
KW   Early protein; Host cell membrane; Host membrane; Membrane; Transmembrane;
KW   Transmembrane helix; Virion.
FT   CHAIN           1..177
FT                   /note="Inner membrane protein p22"
FT                   /id="PRO_0000373366"
FT   TOPO_DOM        1..7
FT                   /note="Intravirion"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        8..28
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        29..177
FT                   /note="Virion surface"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   177 AA;  20176 MW;  0EF6D63417EF35FA CRC64;
     MFNIKMTISV LLIALIVLLI IILVVFLYYK KQQPPKKVCK VDKDCGSGEH CVRGSCSSLS
     CLDAVKTDKR NIKIDSKISS CEFTPNFYRF TDTAADEQQE FGKTRRPIKI TPSPSESHSP
     QEVCERYCSW GTDDCTGWEY EGNEKEGTCY IYNNPHHPVL KYGKDHVIAL PRNHKHA