ID   P22_BORBN               Reviewed;         194 AA.
AC   E4QEX4; P0C924; Q05903; Q45008;
DT   05-APR-2011, integrated into UniProtKB/Swiss-Prot.
DT   08-FEB-2011, sequence version 1.
DT   25-MAY-2022, entry version 40.
DE   RecName: Full=Outer surface 22 kDa lipoprotein;
DE   AltName: Full=Antigen IPLA7;
DE   Flags: Precursor;
GN   Name=p22; OrderedLocusNames=BbuN40_0365;
OS   Borreliella burgdorferi (strain N40) (Borrelia burgdorferi).
OC   Bacteria; Spirochaetes; Spirochaetales; Borreliaceae; Borreliella.
OX   NCBI_TaxID=521007;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=N40;
RX   PubMed=8027338; DOI=10.1128/jcm.32.4.876-883.1994;
RA   Lam T., Nguyen T., Fikrig E., Flavell R.;
RT   "A chromosomal Borrelia burgdorferi gene encodes a 22-kilodalton
RT   lipoprotein, P22, that is serologically recognized in Lyme disease.";
RL   J. Clin. Microbiol. 32:876-883(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=N40;
RX   PubMed=20935092; DOI=10.1128/jb.01158-10;
RA   Schutzer S.E., Fraser-Liggett C.M., Casjens S.R., Qiu W.G., Dunn J.J.,
RA   Mongodin E.F., Luft B.J.;
RT   "Whole-genome sequences of thirteen isolates of Borrelia burgdorferi.";
RL   J. Bacteriol. 193:1018-1020(2011).
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane; Lipid-anchor.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; L22530; AAC36908.1; -; Genomic_DNA.
DR   EMBL; CP002228; ADQ29796.1; -; Genomic_DNA.
DR   PIR; D70145; D70145.
DR   RefSeq; WP_002660648.1; NC_017418.1.
DR   AlphaFoldDB; E4QEX4; -.
DR   SMR; E4QEX4; -.
DR   KEGG; bbn:BbuN40_0365; -.
DR   PATRIC; fig|521007.3.peg.408; -.
DR   HOGENOM; CLU_1400113_0_0_12; -.
DR   OMA; VHSKNDR; -.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   4: Predicted;
KW   Cell outer membrane; Lipoprotein; Membrane; Palmitate; Signal.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000305"
FT   CHAIN           22..194
FT                   /note="Outer surface 22 kDa lipoprotein"
FT                   /id="PRO_0000406314"
FT   LIPID           22
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000305"
FT   LIPID           22
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   194 AA;  21823 MW;  D6E2A03AE701A5BC CRC64;
     MYKNGFFKNY LSLLLIFLVI ACTSKDSSNE YVEEQEAENS SKPDDSKIDE HTIGHVFHAM
     GVVHSKKDRK SLGENIKVFY FSEEDGHFQT IPSKENAKLI VYFYDNVYAG EAPISISGKE
     AFIFVGITSD FKKIINSNLH GAKSDLIGTF KDLNIKNSKL EITVDENNSD AKTFLESVNY
     IIDGVEKISP MLTN