ID   P22_BORBU               Reviewed;         194 AA.
AC   P0CL67; P0C924; Q05903; Q45008;
DT   05-APR-2011, integrated into UniProtKB/Swiss-Prot.
DT   05-APR-2011, sequence version 1.
DT   25-MAY-2022, entry version 40.
DE   RecName: Full=Outer surface 22 kDa lipoprotein;
DE   AltName: Full=Antigen IPLA7;
DE   Flags: Precursor;
GN   Name=p22; OrderedLocusNames=BB_0365;
OS   Borreliella burgdorferi (strain ATCC 35210 / DSM 4680 / CIP 102532 / B31)
OS   (Borrelia burgdorferi).
OC   Bacteria; Spirochaetes; Spirochaetales; Borreliaceae; Borreliella.
OX   NCBI_TaxID=224326;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35210 / DSM 4680 / CIP 102532 / B31;
RX   PubMed=9403685; DOI=10.1038/37551;
RA   Fraser C.M., Casjens S., Huang W.M., Sutton G.G., Clayton R.A.,
RA   Lathigra R., White O., Ketchum K.A., Dodson R.J., Hickey E.K., Gwinn M.L.,
RA   Dougherty B.A., Tomb J.-F., Fleischmann R.D., Richardson D.L.,
RA   Peterson J.D., Kerlavage A.R., Quackenbush J., Salzberg S.L., Hanson M.,
RA   van Vugt R., Palmer N., Adams M.D., Gocayne J.D., Weidman J.F.,
RA   Utterback T.R., Watthey L., McDonald L.A., Artiach P., Bowman C.,
RA   Garland S.A., Fujii C., Cotton M.D., Horst K., Roberts K.M., Hatch B.,
RA   Smith H.O., Venter J.C.;
RT   "Genomic sequence of a Lyme disease spirochaete, Borrelia burgdorferi.";
RL   Nature 390:580-586(1997).
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane; Lipid-anchor.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE000783; AAC66748.1; -; Genomic_DNA.
DR   PIR; D70145; D70145.
DR   RefSeq; NP_212499.1; NC_001318.1.
DR   RefSeq; WP_002657819.1; NC_001318.1.
DR   PDB; 6R1G; X-ray; 1.55 A; A/B=28-194.
DR   PDBsum; 6R1G; -.
DR   AlphaFoldDB; P0CL67; -.
DR   SMR; P0CL67; -.
DR   EnsemblBacteria; AAC66748; AAC66748; BB_0365.
DR   GeneID; 56567793; -.
DR   KEGG; bbu:BB_0365; -.
DR   PATRIC; fig|224326.49.peg.760; -.
DR   HOGENOM; CLU_1400113_0_0_12; -.
DR   OMA; VHSKNDR; -.
DR   Proteomes; UP000001807; Chromosome.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016020; C:membrane; IDA:CAFA.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Cell outer membrane; Lipoprotein; Membrane; Palmitate;
KW   Reference proteome; Signal.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000305"
FT   CHAIN           22..194
FT                   /note="Outer surface 22 kDa lipoprotein"
FT                   /id="PRO_0000018085"
FT   LIPID           22
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000305"
FT   LIPID           22
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000305"
FT   HELIX           50..60
FT                   /evidence="ECO:0007829|PDB:6R1G"
FT   HELIX           66..68
FT                   /evidence="ECO:0007829|PDB:6R1G"
FT   HELIX           69..73
FT                   /evidence="ECO:0007829|PDB:6R1G"
FT   STRAND          77..84
FT                   /evidence="ECO:0007829|PDB:6R1G"
FT   STRAND          87..94
FT                   /evidence="ECO:0007829|PDB:6R1G"
FT   STRAND          98..104
FT                   /evidence="ECO:0007829|PDB:6R1G"
FT   STRAND          107..116
FT                   /evidence="ECO:0007829|PDB:6R1G"
FT   STRAND          119..127
FT                   /evidence="ECO:0007829|PDB:6R1G"
FT   STRAND          131..142
FT                   /evidence="ECO:0007829|PDB:6R1G"
FT   HELIX           145..148
FT                   /evidence="ECO:0007829|PDB:6R1G"
FT   STRAND          150..152
FT                   /evidence="ECO:0007829|PDB:6R1G"
FT   STRAND          154..156
FT                   /evidence="ECO:0007829|PDB:6R1G"
FT   HELIX           169..188
FT                   /evidence="ECO:0007829|PDB:6R1G"
FT   HELIX           189..191
FT                   /evidence="ECO:0007829|PDB:6R1G"
SQ   SEQUENCE   194 AA;  21866 MW;  D42A7CE0E26811B6 CRC64;
     MYKNGFFKNY LSLFLIFLVI ACTSKDSSNE YVEEQEAENS SKPDDSKIDE HTIGHVFHAM
     GVVHSKKDRK SLGKNIKVFY FSEEDGHFQT IPSKENAKLI VYFYDNVYAG EAPISISGKE
     AFIFVGITPD FKKIINSNLH GAKSDLIGTF KDLNIKNSKL EITVDENNSD AKTFLESVNY
     IIDGVEKISP MLTN