P23A3_MOUSE
ID P23A3_MOUSE Reviewed; 254 AA.
AC Q9CWP9;
DT 29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 91.
DE RecName: Full=Proline-rich protein 23A3 {ECO:0000312|MGI:MGI:1919229};
GN Name=Prr23a3 {ECO:0000312|MGI:MGI:1919229};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- SIMILARITY: Belongs to the PRR23 family. {ECO:0000305}.
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DR EMBL; AK010476; BAB26969.1; -; mRNA.
DR EMBL; BC128017; AAI28018.1; -; mRNA.
DR CCDS; CCDS52896.1; -.
DR RefSeq; NP_082309.1; NM_028033.1.
DR AlphaFoldDB; Q9CWP9; -.
DR PhosphoSitePlus; Q9CWP9; -.
DR PaxDb; Q9CWP9; -.
DR PRIDE; Q9CWP9; -.
DR Ensembl; ENSMUST00000167951; ENSMUSP00000130716; ENSMUSG00000090470.
DR GeneID; 71979; -.
DR KEGG; mmu:71979; -.
DR UCSC; uc012gyw.1; mouse.
DR CTD; 71979; -.
DR MGI; MGI:1919229; Prr23a3.
DR VEuPathDB; HostDB:ENSMUSG00000090470; -.
DR eggNOG; ENOG502RU0G; Eukaryota.
DR GeneTree; ENSGT00390000007772; -.
DR HOGENOM; CLU_090685_0_0_1; -.
DR InParanoid; Q9CWP9; -.
DR OMA; MFIPYRE; -.
DR OrthoDB; 1423797at2759; -.
DR PhylomeDB; Q9CWP9; -.
DR TreeFam; TF338612; -.
DR BioGRID-ORCS; 71979; 0 hits in 39 CRISPR screens.
DR PRO; PR:Q9CWP9; -.
DR Proteomes; UP000000589; Chromosome 9.
DR RNAct; Q9CWP9; protein.
DR Bgee; ENSMUSG00000090470; Expressed in secondary oocyte and 10 other tissues.
DR Genevisible; Q9CWP9; MM.
DR InterPro; IPR018903; PRR23.
DR Pfam; PF10630; DUF2476; 1.
PE 2: Evidence at transcript level;
KW Reference proteome.
FT CHAIN 1..254
FT /note="Proline-rich protein 23A3"
FT /id="PRO_0000332253"
FT REGION 1..50
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 161..196
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 212..254
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 166..193
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 215..242
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 254 AA; 27565 MW; 7DAAD882EA19C605 CRC64;
MLRTRPRSPS ADPAPCWSPQ TPAPSPAKRR RLHQEPACPE PLAQPELEAP AEPTTSVVFL
AAGSALQLPL DGVDLLLEPE PTSVLQVSLQ GHTILLVPEG LQDSTHFGQP GFVAISPQGA
AAQDGPQDHL VGLQEETFCE YFYQEDVCDE DADLEFLEHW ASPPDDQANG NFSSIPGVPS
PLSQDQVPGP STGAEQYSPR FIWELDINML GPFPGSPLQP LPPSPSRNPQ EQLPPCPPCS
PRAPRRARKR LVYE
