ID   P23_THEPA               Reviewed;         229 AA.
AC   Q4N4T9;
DT   18-APR-2006, integrated into UniProtKB/Swiss-Prot.
DT   02-AUG-2005, sequence version 1.
DT   25-MAY-2022, entry version 39.
DE   RecName: Full=23 kDa piroplasm membrane protein;
DE   AltName: Full=p23;
DE   Flags: Precursor;
GN   OrderedLocusNames=TP02_0551;
OS   Theileria parva (East coast fever infection agent).
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Piroplasmida;
OC   Theileriidae; Theileria.
OX   NCBI_TaxID=5875;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Muguga;
RX   PubMed=15994558; DOI=10.1126/science.1110439;
RA   Gardner M.J., Bishop R., Shah T., de Villiers E.P., Carlton J.M., Hall N.,
RA   Ren Q., Paulsen I.T., Pain A., Berriman M., Wilson R.J.M., Sato S.,
RA   Ralph S.A., Mann D.J., Xiong Z., Shallom S.J., Weidman J., Jiang L.,
RA   Lynn J., Weaver B., Shoaibi A., Domingo A.R., Wasawo D., Crabtree J.,
RA   Wortman J.R., Haas B., Angiuoli S.V., Creasy T.H., Lu C., Suh B.,
RA   Silva J.C., Utterback T.R., Feldblyum T.V., Pertea M., Allen J.,
RA   Nierman W.C., Taracha E.L.N., Salzberg S.L., White O.R., Fitzhugh H.A.,
RA   Morzaria S., Venter J.C., Fraser C.M., Nene V.;
RT   "Genome sequence of Theileria parva, a bovine pathogen that transforms
RT   lymphocytes.";
RL   Science 309:134-137(2005).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; AAGK01000002; EAN32834.1; -; Genomic_DNA.
DR   RefSeq; XP_765117.1; XM_760024.1.
DR   AlphaFoldDB; Q4N4T9; -.
DR   SMR; Q4N4T9; -.
DR   STRING; 5875.XP_765117.1; -.
DR   PRIDE; Q4N4T9; -.
DR   EnsemblProtists; EAN32834; EAN32834; TP02_0551.
DR   GeneID; 3502172; -.
DR   KEGG; tpv:TP02_0551; -.
DR   VEuPathDB; PiroplasmaDB:TpMuguga_02g00551; -.
DR   eggNOG; ENOG502QXG2; Eukaryota.
DR   InParanoid; Q4N4T9; -.
DR   OMA; KKEGWEY; -.
DR   Proteomes; UP000001949; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome; Signal; Transmembrane; Transmembrane helix.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000255"
FT   CHAIN           20..229
FT                   /note="23 kDa piroplasm membrane protein"
FT                   /id="PRO_0000232717"
FT   TOPO_DOM        20..203
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        204..224
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        225..229
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   229 AA;  27074 MW;  CD08066802C57EFB CRC64;
     MNKYFKVFFF VLLTHALKSA LIFGQATLQK GLSLDIDKDS KATDRLVVKH FDSDKQGYKA
     YTFKKEGWEY VNVKHVYFGE RLLRVGRDQD MKCDYVHYVK VFWKGELAPF LIKMKYYNWA
     WVSTRLHFRL TPELTWAEVF VPTIDENSEE GYMKLFKKRM DDFVSQVGED RLATYKPFTE
     DPSKKRFDLT PTDEKEDTNK KKYVLMVVVV VVFVVVASLV VFLVKFCLK