ID   P28B_VACCW              Reviewed;          62 AA.
AC   Q805K3;
DT   21-SEP-2011, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   23-FEB-2022, entry version 67.
DE   RecName: Full=Zinc finger-containing protein P28b;
GN   OrderedLocusNames=VACWR012;
GN   and
GN   OrderedLocusNames=VACWR207;
OS   Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain
OS   WR)).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus; Vaccinia virus.
OX   NCBI_TaxID=10254;
OH   NCBI_TaxID=9913; Bos taurus (Bovine).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Esposito J.J., Frace A.M., Sammons S.A., Olsen-Rasmussen M., Osborne J.,
RA   Wohlhueter R.;
RT   "Sequencing of the coding region of Vaccinia-WR to an average 9-fold
RT   redundancy and an error rate of 0.16/10kb.";
RL   Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- DOMAIN: The RING-CH-type zinc finger domain is required for E3 ligase
CC       activity. {ECO:0000250}.
CC   -!- MISCELLANEOUS: Encodes the C-terminal region of the E3 ubiquitin ligase
CC       p28 protein present in variola virus.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AY243312; AAO89291.1; -; Genomic_DNA.
DR   EMBL; AY243312; AAO89486.1; -; Genomic_DNA.
DR   RefSeq; YP_232894.1; NC_006998.1.
DR   RefSeq; YP_233089.1; NC_006998.1.
DR   SMR; Q805K3; -.
DR   DNASU; 3707627; -.
DR   GeneID; 3707584; -.
DR   GeneID; 3707627; -.
DR   KEGG; vg:3707584; -.
DR   KEGG; vg:3707627; -.
DR   Proteomes; UP000000344; Genome.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.40.10; -; 1.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   InterPro; IPR017907; Znf_RING_CS.
DR   Pfam; PF13639; zf-RING_2; 1.
DR   PROSITE; PS00518; ZF_RING_1; 1.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   3: Inferred from homology;
KW   Ligase; Metal-binding; Reference proteome; Ubl conjugation pathway; Zinc;
KW   Zinc-finger.
FT   CHAIN           1..62
FT                   /note="Zinc finger-containing protein P28b"
FT                   /id="PRO_0000412617"
FT   ZN_FING         1..46
FT                   /note="RING-type; degenerate"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00175"
SQ   SEQUENCE   62 AA;  7424 MW;  A9E865468FBB4826 CRC64;
     MKLFTQNDRY FGLLDSCTHI FCITCINIWH KTRRETGASD NCPICRTRFR NITMSKFYKL
     VN