ID   P28_VACCW               Reviewed;         184 AA.
AC   P17366; Q76ZK0; Q80HY8;
DT   01-AUG-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1990, sequence version 1.
DT   02-JUN-2021, entry version 54.
DE   RecName: Full=Truncated p28 protein;
GN   Name=p28; OrderedLocusNames=VACWR208;
GN   and
GN   OrderedLocusNames=VACWR011;
OS   Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain
OS   WR)).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus; Vaccinia virus.
OX   NCBI_TaxID=10254;
OH   NCBI_TaxID=9913; Bos taurus (Bovine).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2849238; DOI=10.1016/s0042-6822(88)90115-8;
RA   Kotwal G.J., Moss B.;
RT   "Analysis of a large cluster of nonessential genes deleted from a vaccinia
RT   virus terminal transposition mutant.";
RL   Virology 167:524-537(1988).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Esposito J.J., Frace A.M., Sammons S.A., Olsen-Rasmussen M., Osborne J.,
RA   Wohlhueter R.;
RT   "Sequencing of the coding region of Vaccinia-WR to an average 9-fold
RT   redundancy and an error rate of 0.16/10kb.";
RL   Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- MISCELLANEOUS: Encodes a truncated version of the E3 ubiquitin ligase
CC       p28 protein present in variola virus. Lacks the C-terminal region
CC       containing the RING-type zinc-finger. The absence of RING-type zinc-
CC       finger in several attenuated vaccinia strains, demonstrates the
CC       importance of this domain in virulence.
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DR   EMBL; M22812; AAA69592.1; -; Genomic_DNA.
DR   EMBL; AY243312; AAO89290.1; -; Genomic_DNA.
DR   EMBL; AY243312; AAO89487.1; -; Genomic_DNA.
DR   PIR; A31829; WZVZA1.
DR   RefSeq; YP_233090.1; NC_006998.1.
DR   DNASU; 3707585; -.
DR   GeneID; 3707585; -.
DR   KEGG; vg:3707585; -.
DR   Proteomes; UP000000344; Genome.
DR   InterPro; IPR017880; KilA_N.
DR   InterPro; IPR018004; KilA_N/APSES_HTH.
DR   Pfam; PF04383; KilA-N; 1.
DR   PROSITE; PS51301; KILA_N; 1.
PE   4: Predicted;
KW   Early protein; Reference proteome.
FT   CHAIN           1..184
FT                   /note="Truncated p28 protein"
FT                   /id="PRO_0000099742"
FT   DOMAIN          21..131
FT                   /note="KilA-N"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00631"
FT   CONFLICT        141..143
FT                   /note="Missing (in Ref. 2; AAO89290)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   184 AA;  21604 MW;  E8CCCCDB5529B293 CRC64;
     MEFDPAKINT SSIDHVTILQ YIDEPNDIRL TVCIIRNINN ITYYINITKI NTHLANQFRA
     WKKRIAGRDY MTNLSRDTGI QQSKLTETIR NCQKNRNIYG LYIHYNLVIN VVIDWITDVI
     VQSILRGLVN WYIANNTYTP NTPNNTTTIS ELDIIKILDK YEDVYRVSKE KECGICYEVV
     YSKR