P2B10_ARATH
ID P2B10_ARATH Reviewed; 272 AA.
AC Q9ZVQ6;
DT 23-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1999, sequence version 1.
DT 25-MAY-2022, entry version 116.
DE RecName: Full=F-box protein PP2-B10;
DE AltName: Full=Protein PHLOEM PROTEIN 2-LIKE B10;
DE Short=AtPP2-B10;
GN Name=PP2B10; OrderedLocusNames=At2g02360; ORFNames=T16F16.15;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Kim C.J., Chen H., Quinitio C., Shinn P., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=12529520; DOI=10.1104/pp.013086;
RA Dinant S., Clark A.M., Zhu Y., Vilaine F., Palauqui J.-C., Kusiak C.,
RA Thompson G.A.;
RT "Diversity of the superfamily of phloem lectins (phloem protein 2) in
RT angiosperms.";
RL Plant Physiol. 131:114-128(2003).
RN [6]
RP INTERACTION WITH SKP1B/ASK2; ASK11 AND ASK12.
RX PubMed=14749489; DOI=10.1093/pcp/pch009;
RA Takahashi N., Kuroda H., Kuromori T., Hirayama T., Seki M., Shinozaki K.,
RA Shimada H., Matsui M.;
RT "Expression and interaction analysis of Arabidopsis Skp1-related genes.";
RL Plant Cell Physiol. 45:83-91(2004).
CC -!- FUNCTION: Component of SCF(ASK-cullin-F-box) E3 ubiquitin ligase
CC complexes, which may mediate the ubiquitination and subsequent
CC proteasomal degradation of target proteins. {ECO:0000250}.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC -!- SUBUNIT: Part of a SCF (ASK-cullin-F-box) protein ligase complex (By
CC similarity). Interacts with SKP1B/ASK2, ASK11 and ASK12. {ECO:0000250,
CC ECO:0000269|PubMed:14749489}.
CC -!- DOMAIN: The F-box is necessary for the interaction with ASK proteins.
CC {ECO:0000250}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AC005312; AAC78518.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC05569.1; -; Genomic_DNA.
DR EMBL; BT025799; ABF83689.1; -; mRNA.
DR EMBL; AK227207; BAE99245.1; -; mRNA.
DR PIR; G84435; G84435.
DR RefSeq; NP_178341.1; NM_126293.4.
DR AlphaFoldDB; Q9ZVQ6; -.
DR BioGRID; 170; 4.
DR IntAct; Q9ZVQ6; 4.
DR STRING; 3702.AT2G02360.1; -.
DR PaxDb; Q9ZVQ6; -.
DR PRIDE; Q9ZVQ6; -.
DR ProteomicsDB; 248695; -.
DR DNASU; 814767; -.
DR EnsemblPlants; AT2G02360.1; AT2G02360.1; AT2G02360.
DR GeneID; 814767; -.
DR Gramene; AT2G02360.1; AT2G02360.1; AT2G02360.
DR KEGG; ath:AT2G02360; -.
DR Araport; AT2G02360; -.
DR TAIR; locus:2056231; AT2G02360.
DR eggNOG; ENOG502QRA4; Eukaryota.
DR HOGENOM; CLU_050973_0_0_1; -.
DR InParanoid; Q9ZVQ6; -.
DR OMA; AYWRWIS; -.
DR OrthoDB; 1051457at2759; -.
DR PhylomeDB; Q9ZVQ6; -.
DR UniPathway; UPA00143; -.
DR PRO; PR:Q9ZVQ6; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q9ZVQ6; baseline and differential.
DR Genevisible; Q9ZVQ6; AT.
DR GO; GO:0030246; F:carbohydrate binding; IDA:TAIR.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR InterPro; IPR036047; F-box-like_dom_sf.
DR InterPro; IPR001810; F-box_dom.
DR InterPro; IPR025886; PP2-like.
DR Pfam; PF00646; F-box; 1.
DR Pfam; PF14299; PP2; 1.
DR SMART; SM00256; FBOX; 1.
DR SUPFAM; SSF81383; SSF81383; 1.
DR PROSITE; PS50181; FBOX; 1.
PE 1: Evidence at protein level;
KW Reference proteome; Ubl conjugation pathway.
FT CHAIN 1..272
FT /note="F-box protein PP2-B10"
FT /id="PRO_0000272218"
FT DOMAIN 11..57
FT /note="F-box"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00080"
SQ SEQUENCE 272 AA; 31294 MW; 4A9F642DADE76FBA CRC64;
MGRKRRVKSE SSPFDSFPED CISYIISFTN PRDACVAATV SKTFESTVKS DIIWEKFLPA
DYESLIPPSR VFSSKKELYF SLCNDPVLFD DDKKSVWLEK ASGKRCLMLS AMNLSIIWGD
NPQYWQWIPI PESRFEKVAK LRDVCWFEIR GRTNTRVLSP RTRYSAYIVF KGVDKCYGFQ
NVAIEAAVGV VGQEPSRRLI CFSEAIRRGR RNVVKPKQRE DGWMEIELGE FFNDGGIMDN
DEIEMSALET KQLNRKCGLI IQGIEIRPAK IL
